| 1. Jornada | 05.06.2022 | Independiente II | - | San Lorenzo II | 0:1 | ||||
| 2. Jornada | 09.06.2022 | San Lorenzo II | - | Newell's Old Boys II | 2:3 | ||||
| 3. Jornada | 14.06.2022 | Arsenal de Sarandí II | - | San Lorenzo II | 0:1 | ||||
| 6. Jornada | 03.07.2022 | San Lorenzo II | - | Barracas Central II | 1:0 | ||||
| 16. Jornada | 28.08.2022 | Rosario Central II | - | San Lorenzo II | 0:1 |  |
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| 17. Jornada | 01.09.2022 | San Lorenzo II | - | Defensa y Justicia II | 1:0 | ||||
| 18. Jornada | 07.09.2022 | Atlético Tucumán II | - | San Lorenzo II | 1:2 | ||||
| 19. Jornada | 12.09.2022 | San Lorenzo II | - | Colón de Santa Fe II | 2:1 | ||||
| 20. Jornada | 19.09.2022 | River Plate II | - | San Lorenzo II | 1:0 | ||||
| 21. Jornada | 25.09.2022 | San Lorenzo II | - | Lanús II | 1:2 | |
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| 22. Jornada | 28.09.2022 | Huracán II | - | San Lorenzo II | 3:1 | ||||
| 23. Jornada | 04.10.2022 | San Lorenzo II | - | Godoy Cruz II | 0:1 | ||||
| 24. Jornada | 10.10.2022 | Vélez Sarsfield II | - | San Lorenzo II | 2:0 |
Argentina