| 3. Jornada | 27.07.2021 | Newell's Old Boys II | - | Estudiantes II | 1:3 | ||||
| 4. Jornada | 30.07.2021 | Patronato de Paraná II | - | Newell's Old Boys II | 1:2 | ||||
| 5. Jornada | 06.08.2021 | Newell's Old Boys II | - | Platense II | 1:2 | ||||
| 7. Jornada | 20.08.2021 | Newell's Old Boys II | - | Rosario Central II | 1:1 | ||||
| 8. Jornada | 24.08.2021 | Defensa y Justicia II | - | Newell's Old Boys II | 1:1 | ||||
| 9. Jornada | 30.08.2021 | Newell's Old Boys II | - | Atlético Tucumán II | 2:3 | ||||
| 14. Jornada | 01.10.2021 | Godoy Cruz II | - | Newell's Old Boys II | 1:1 | ||||
| 16. Jornada | 14.10.2021 | Gimnasia de La Plata II | - | Newell's Old Boys II | 1:1 | ||||
| 17. Jornada | 18.10.2021 | Newell's Old Boys II | - | Aldosivi II | 1:0 | ||||
| 18. Jornada | 22.10.2021 | Sarmiento de Junín II | - | Newell's Old Boys II | 1:2 | ||||
| 22. Jornada | 24.11.2021 | Newell's Old Boys II | - | Central Córdoba SdE II | 1:1 |
Argentina