| 1. Jornada | 07.08.2021 | Lyon (CFA) | - | Mónaco (CFA) | 1:0 | ||||
| 2. Jornada | 14.08.2021 | FC Martigues | - | Lyon (CFA) | 1:1 |  |
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| 3. Jornada | 21.08.2021 | Lyon (CFA) | - | GFA Rumilly Vallières | 0:2 | ||||
| 4. Jornada | 28.08.2021 | AS Saint-Priest | - | Lyon (CFA) | 1:3 | |
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| 5. Jornada | 04.09.2021 | Lyon (CFA) | - | Étoile FC | 3:0 | |
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| 6. Jornada | 11.09.2021 | GOAL FC | - | Lyon (CFA) | 2:0 | ||||
| 8. Jornada | 25.09.2021 | Jura Sud | - | Lyon (CFA) | 1:1 | ||||
| 9. Jornada | 09.10.2021 | Lyon (CFA) | - | Marsella (CFA) | 2:2 |  |
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| 10. Jornada | 23.10.2021 | Marignane Gignac FC | - | Lyon (CFA) | 4:0 | ||||
| 14. Jornada | 11.12.2021 | Lyon (CFA) | - | Hyères FC | 3:2 | ||||
| 13. Jornada | 18.12.2021 | Louhans-Cuiseaux | - | Lyon (CFA) | 1:2 | ||||
| 16. Jornada | 22.01.2022 | Lyon (CFA) | - | FC Martigues | 0:1 | ||||
| 15. Jornada | 26.01.2022 | Lyon-La Duchère | - | Lyon (CFA) | 0:0 | ||||
| 20. Jornada | 05.03.2022 | Lyon (CFA) | - | GOAL FC | 0:2 | ||||
| 22. Jornada | 19.03.2022 | Lyon (CFA) | - | Jura Sud | 0:4 |
Francia
Togo 
