| 2. Jornada | 15.01.2022 | Club León [Sub 16] | - | UANL Tigres [Sub 16] | 0:1 | ||||
| 3. Jornada | 22.01.2022 | UANL Tigres [Sub 16] | - | Santos Laguna [Sub 16] | 0:2 | ||||
| 9. Jornada | 05.03.2022 | Atlético San Luis [Sub 16] | - | UANL Tigres [Sub 16] | 1:1 | ||||
| 12. Jornada | 26.03.2022 | Club Tijuana [Sub 16] | - | UANL Tigres [Sub 16] | 2:1 | ||||
| 14. Jornada | 27.04.2022 | CF Monterrey [Sub 16] | - | UANL Tigres [Sub 16] | 2:3 | ||||
| 17. Jornada | 30.04.2022 | UANL Tigres [Sub 16] | - | Atlas Guadalajara [Sub 16] | 2:2 | ||||
| 18. Jornada | 07.05.2022 | Deportivo Guadalajara [Sub 16] | - | UANL Tigres [Sub 16] | 4:3 |
México