| 1. Jornada | 07.02.2022 | Royal Pari | - | Jorge Wilstermann | 0:2 |  |
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| 2. Jornada | 12.02.2022 | Jorge Wilstermann | - | Blooming | 0:1 | ||||
| 3. Jornada | 20.02.2022 | Universitario de Vinto | - | Jorge Wilstermann | 2:0 | ||||
| 4. Jornada | 28.02.2022 | Jorge Wilstermann | - | Independiente Petrolero | 1:0 | ||||
| 5. Jornada | 06.03.2022 | Always Ready | - | Jorge Wilstermann | 0:0 | ||||
| 7. Jornada | 02.04.2022 | Jorge Wilstermann | - | Real Tomayapo | 1:2 | ||||
| 8. Jornada | 09.04.2022 | Bolívar | - | Jorge Wilstermann | 0:1 | ||||
| 9. Jornada | 17.04.2022 | Jorge Wilstermann | - | Royal Pari | 2:2 | ||||
| 11. Jornada | 23.04.2022 | Jorge Wilstermann | - | Universitario de Vinto | 1:1 | ||||
| 12. Jornada | 01.05.2022 | Independiente Petrolero | - | Jorge Wilstermann | 3:2 | |
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| 16. Jornada | 22.05.2022 | Jorge Wilstermann | - | Bolívar | 1:4 |
Bolivia