| 10. Jornada | 23.10.2021 | Guingamp (CFA) | - | AS Poissy | 1:1 | ||||
| 12. Jornada | 20.11.2021 | Guingamp (CFA) | - | Châteaubriant Voltigeurs | 2:3 | ||||
| 15. Jornada | 15.01.2022 | SO Romorantin | - | Guingamp (CFA) | 2:3 | ||||
| 16. Jornada | 22.01.2022 | Guingamp (CFA) | - | AS Vitré | 0:5 | ||||
| 13. Jornada | 26.01.2022 | Vannes OC | - | Guingamp (CFA) | 2:0 | ||||
| 18. Jornada | 12.02.2022 | Guingamp (CFA) | - | US Saint-Malo | 0:0 | ||||
| 20. Jornada | 05.03.2022 | Guingamp (CFA) | - | St-Pryvé St-Hilaire | 1:1 | ||||
| 21. Jornada | 12.03.2022 | Blois Foot 41 | - | Guingamp (CFA) | 5:2 | ||||
| 22. Jornada | 19.03.2022 | Guingamp (CFA) | - | Lorient (CFA) | 1:2 | ||||
| 29. Jornada | 21.05.2022 | Guingamp (CFA) | - | SO Romorantin | 1:2 |
Francia