| 1. Jornada | 25.07.2010 | Club San Luis | - | CF Monterrey | 1:1 |  |
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| 2. Jornada | 01.08.2010 | CF Monterrey | - | Estudiantes Tecos | 3:2 | |
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| 3. Jornada | 08.08.2010 | Atlante | - | CF Monterrey | 1:2 | ||||
| 4. Jornada | 15.08.2010 | CF Monterrey | - | Pumas UNAM | 5:2 | |
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| 5. Jornada | 22.08.2010 | CF Pachuca | - | CF Monterrey | 2:2 | |
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| 6. Jornada | 29.08.2010 | CF Monterrey | - | Jaguares Chiapas | 1:1 | |
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| 7. Jornada | 12.09.2010 | UANL Tigres | - | CF Monterrey | 0:1 | |
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| 8. Jornada | 19.09.2010 | CF Monterrey | - | Atlas Guadalajara | 2:0 | |
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| 9. Jornada | 26.09.2010 | Gallos Blancos (old) | - | CF Monterrey | 0:0 | ||||
| 10. Jornada | 03.10.2010 | CF Monterrey | - | Club Necaxa | 2:1 | |
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| 11. Jornada | 10.10.2010 | CF América | - | CF Monterrey | 0:0 | |
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| 12. Jornada | 17.10.2010 | CF Monterrey | - | Deportivo Toluca | 2:0 | |
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| 13. Jornada | 24.10.2010 | Santos Laguna | - | CF Monterrey | 1:2 | |
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| 14. Jornada | 28.10.2010 | CF Monterrey | - | Cruz Azul | 2:4 | ||||
| 17. Jornada | 14.11.2010 | CF Monterrey | - | Deportivo Guadalajara | 2:3 | |
Chile
