| 3. Jornada | 12.09.2020 | Rodez AF | - | Caen | 0:3 | ||||
| 6. Jornada | 03.10.2020 | Caen | - | Amiens SC | 1:0 | ||||
| 18. Jornada | 05.01.2021 | AJ Auxerre | - | Caen | 1:1 | ||||
| 19. Jornada | 11.01.2021 | Caen | - | Toulouse | 2:2 | ||||
| 21. Jornada | 23.01.2021 | Caen | - | Rodez AF | 1:2 | ||||
| 22. Jornada | 30.01.2021 | FC Chambly | - | Caen | 4:2 | ||||
| 23. Jornada | 02.02.2021 | Caen | - | Valenciennes FC | 1:1 | ||||
| 24. Jornada | 05.02.2021 | Amiens SC | - | Caen | 0:0 | ||||
| 25. Jornada | 13.02.2021 | Caen | - | Chamois Niortais | 1:0 | ||||
| 26. Jornada | 22.02.2021 | Guingamp | - | Caen | 2:2 | ||||
| 27. Jornada | 27.02.2021 | Caen | - | Paris FC | 0:2 | ||||
| 28. Jornada | 02.03.2021 | AS Nancy Lorraine | - | Caen | 1:0 | ||||
| 29. Jornada | 15.03.2021 | Caen | - | Havre AC | 0:2 | ||||
| 30. Jornada | 20.03.2021 | LB Châteauroux | - | Caen | 2:2 |  |
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| 31. Jornada | 03.04.2021 | Caen | - | Pau FC | 1:1 | ||||
| 32. Jornada | 10.04.2021 | Grenoble Foot 38 | - | Caen | 3:1 | ||||
| 33. Jornada | 17.04.2021 | Troyes | - | Caen | 1:0 | ||||
| 37. Jornada | 08.05.2021 | Toulouse | - | Caen | 3:0 | ||||
| 38. Jornada | 15.05.2021 | Caen | - | Clermont Foot 63 | 2:1 |
Francia