| 2. Jornada | 15.01.2022 | Cruz Azul [Sub 16] | - | CF Pachuca [Sub 16] | 4:2 | ||||
| 6. Jornada | 12.02.2022 | Club Necaxa [Sub 16] | - | CF Pachuca [Sub 16] | 2:2 | ||||
| 14. Jornada | 09.04.2022 | CF Pachuca [Sub 16] | - | Club Necaxa [Sub 16] | 1:2 | ||||
| 16. Jornada | 23.04.2022 | CF América [Sub 16] | - | CF Pachuca [Sub 16] | 2:0 | ||||
| 17. Jornada | 30.04.2022 | CF Pachuca [Sub 16] | - | Deportivo Toluca [Sub 16] | 0:0 | ||||
| 18. Jornada | 07.05.2022 | Gallos Blancos [Sub 16] | - | CF Pachuca [Sub 16] | 2:2 |
México