| 17. Jornada | 12.02.2022 | FC Rodange 91 | - | Union Titus Pétange | 0:4 | ||||
| 16. Jornada | 16.02.2022 | Union Titus Pétange | - | Swift Hesperange | 0:3 | ||||
| 18. Jornada | 20.02.2022 | Union Titus Pétange | - | RM Hamm Benfica | 3:1 | ||||
| 19. Jornada | 27.02.2022 | FC Wiltz 71 | - | Union Titus Pétange | 3:2 | ||||
| 21. Jornada | 13.03.2022 | Jeunesse Esch | - | Union Titus Pétange | 1:0 | ||||
| 22. Jornada | 19.03.2022 | Union Titus Pétange | - | US Hostert | 3:0 |  |
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| 23. Jornada | 02.04.2022 | RFCU Luxemburg | - | Union Titus Pétange | 0:0 |  |
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| 24. Jornada | 10.04.2022 | Union Titus Pétange | - | Progrès Niedercorn | 0:0 | ||||
| 26. Jornada | 24.04.2022 | Etzella Ettelbruck | - | Union Titus Pétange | 0:1 | ||||
| 27. Jornada | 01.05.2022 | Union Titus Pétange | - | FC Differdange 03 | 1:2 |  |
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| 29. Jornada | 15.05.2022 | Union Titus Pétange | - | CS FOLA Esch | 0:1 | ||||
| 30. Jornada | 22.05.2022 | UNA Strassen | - | Union Titus Pétange | 2:2 | |
Francia