| 1. Jornada | 25.07.2021 | Club Tijuana [Sub 18] | - | UANL Tigres [Sub 18] | 1:0 | ||||
| 2. Jornada | 31.07.2021 | Club León [Sub 18] | - | Club Tijuana [Sub 18] | 2:1 | ||||
| 3. Jornada | 06.08.2021 | Club Tijuana [Sub 18] | - | Deportivo Toluca [Sub 18] | 3:0 | ||||
| 4. Jornada | 13.08.2021 | FC Juárez [Sub 18] | - | Club Tijuana [Sub 18] | 3:2 | ||||
| 5. Jornada | 17.08.2021 | Club Tijuana [Sub 18] | - | Puebla FC [Sub 18] | 5:2 |  |
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| 9. Jornada | 16.09.2021 | Atlético San Luis [Sub 18] | - | Club Tijuana [Sub 18] | 1:0 | ||||
| 10. Jornada | 24.09.2021 | Club Tijuana [Sub 18] | - | Mazatlán FC [Sub 18] | 1:2 | ||||
| 12. Jornada | 03.10.2021 | Club Tijuana [Sub 18] | - | Cruz Azul [Sub 18] | 3:2 | ||||
| 15. Jornada | 24.10.2021 | Pumas UNAM [Sub 18] | - | Club Tijuana [Sub 18] | 2:2 |
México