| 1. Jornada | 24.07.2021 | FC Juárez | - | Deportivo Toluca | 1:3 | ||||
| 7. Jornada | 30.08.2021 | Santos Laguna | - | FC Juárez | 2:0 | ||||
| 8. Jornada | 11.09.2021 | FC Juárez | - | Cruz Azul | 2:1 |  |
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| 9. Jornada | 19.09.2021 | Club León | - | FC Juárez | 0:1 | ||||
| 14. Jornada | 22.09.2021 | FC Juárez | - | Atlético San Luis | 1:0 | ||||
| 11. Jornada | 29.09.2021 | Mazatlán FC | - | FC Juárez | 3:1 | ||||
| 16. Jornada | 30.10.2021 | FC Juárez | - | Puebla FC | 0:2 | ||||
| 17. Jornada | 07.11.2021 | UANL Tigres | - | FC Juárez | 3:0 |
España