| 1. Jornada | 07.08.2021 | Guingamp (CFA) | - | FC Rouen 1899 | 0:0 | ||||
| 2. Jornada | 14.08.2021 | AS Vitré | - | Guingamp (CFA) | 0:4 |  |
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| 3. Jornada | 21.08.2021 | Guingamp (CFA) | - | FC Versailles | 0:3 | ||||
| 4. Jornada | 28.08.2021 | US Saint-Malo | - | Guingamp (CFA) | 0:2 | ||||
| 8. Jornada | 25.09.2021 | Lorient (CFA) | - | Guingamp (CFA) | 3:0 | ||||
| 9. Jornada | 09.10.2021 | Guingamp (CFA) | - | Caen (CFA) | 1:1 | ||||
| 10. Jornada | 23.10.2021 | Guingamp (CFA) | - | AS Poissy | 1:1 | |
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| 11. Jornada | 06.11.2021 | C'Chartres Football | - | Guingamp (CFA) | 1:2 | ||||
| 12. Jornada | 20.11.2021 | Guingamp (CFA) | - | Châteaubriant Voltigeurs | 2:3 | ||||
| 15. Jornada | 15.01.2022 | SO Romorantin | - | Guingamp (CFA) | 2:3 | ||||
| 16. Jornada | 22.01.2022 | Guingamp (CFA) | - | AS Vitré | 0:5 | ||||
| 17. Jornada | 05.02.2022 | FC Versailles | - | Guingamp (CFA) | 1:1 | ||||
| 18. Jornada | 12.02.2022 | Guingamp (CFA) | - | US Saint-Malo | 0:0 | ||||
| 19. Jornada | 19.02.2022 | Stade Plabennec | - | Guingamp (CFA) | 1:0 | ||||
| 23. Jornada | 26.03.2022 | Caen (CFA) | - | Guingamp (CFA) | 0:2 | ||||
| 24. Jornada | 09.04.2022 | AS Poissy | - | Guingamp (CFA) | 1:1 |
Francia
Argelia