| 6. Jornada | 11.09.2021 | AS Vitré | - | Vannes OC | 0:1 | ||||
| 7. Jornada | 18.09.2021 | Vannes OC | - | FC Versailles | 0:1 | ||||
| 9. Jornada | 09.10.2021 | Vannes OC | - | Stade Plabennec | 1:1 | ||||
| 11. Jornada | 07.11.2021 | Vannes OC | - | Blois Foot 41 | 2:2 |  |
|||
| 16. Jornada | 22.01.2022 | Vannes OC | - | Caen (CFA) | 1:4 | ||||
| 13. Jornada | 26.01.2022 | Vannes OC | - | Guingamp (CFA) | 2:0 | ||||
| 15. Jornada | 29.01.2022 | Vannes OC | - | C'Chartres Football | 2:3 | ||||
| 17. Jornada | 05.02.2022 | US Granvillaise | - | Vannes OC | 1:2 | ||||
| 18. Jornada | 12.02.2022 | Vannes OC | - | SO Romorantin | 3:1 | ||||
| 19. Jornada | 18.02.2022 | FC Rouen 1899 | - | Vannes OC | 0:2 | ||||
| 20. Jornada | 05.03.2022 | Vannes OC | - | AS Vitré | 3:1 | ||||
| 21. Jornada | 12.03.2022 | FC Versailles | - | Vannes OC | 1:0 | ||||
| 22. Jornada | 19.03.2022 | Vannes OC | - | US Saint-Malo | 3:2 | ||||
| 25. Jornada | 16.04.2022 | Blois Foot 41 | - | Vannes OC | 5:2 | ||||
| 26. Jornada | 23.04.2022 | Vannes OC | - | Lorient (CFA) | 0:3 |  |
Benin