| 4. Jornada | 20.08.2022 | Caen | - | Guingamp | 4:1 |  |
 |
||
| 9. Jornada | 17.09.2022 | Guingamp | - | Saint-Étienne | 2:1 | ||||
| 7. Jornada | 04.10.2022 | Guingamp | - | Rodez AF | 0:0 | ||||
| 11. Jornada | 08.10.2022 | Guingamp | - | FC Annecy | 0:4 | ||||
| 12. Jornada | 15.10.2022 | Valenciennes FC | - | Guingamp | 1:0 | ||||
| 15. Jornada | 12.11.2022 | Guingamp | - | Havre AC | 0:1 | ||||
| 16. Jornada | 26.12.2022 | Nîmes Olympique | - | Guingamp | 1:2 | ||||
| 18. Jornada | 10.01.2023 | Amiens SC | - | Guingamp | 1:1 | ||||
| 19. Jornada | 13.01.2023 | Guingamp | - | Grenoble Foot 38 | 2:4 | |
|||
| 21. Jornada | 31.01.2023 | Guingamp | - | Nîmes Olympique | 1:2 | ||||
| 22. Jornada | 03.02.2023 | US Quevilly-Rouen | - | Guingamp | 2:0 | |
Malí