| 17. Jornada | 05.02.2022 | US Saint-Malo | - | Lorient (CFA) | 2:0 | ||||
| 18. Jornada | 12.02.2022 | Guingamp (CFA) | - | US Saint-Malo | 0:0 | ||||
| 19. Jornada | 19.02.2022 | US Saint-Malo | - | AS Poissy | 2:0 |  |
|||
| 20. Jornada | 05.03.2022 | C'Chartres Football | - | US Saint-Malo | 2:1 | ||||
| 21. Jornada | 12.03.2022 | US Saint-Malo | - | Châteaubriant Voltigeurs | 3:2 |  |
|||
| 22. Jornada | 19.03.2022 | Vannes OC | - | US Saint-Malo | 3:2 | |
|||
| 23. Jornada | 26.03.2022 | US Saint-Malo | - | US Granvillaise | 1:0 | ||||
| 24. Jornada | 09.04.2022 | SO Romorantin | - | US Saint-Malo | 2:1 | |
|||
| 25. Jornada | 16.04.2022 | US Saint-Malo | - | FC Rouen 1899 | 1:4 | ||||
| 26. Jornada | 23.04.2022 | AS Vitré | - | US Saint-Malo | 2:2 | |
|||
| 27. Jornada | 30.04.2022 | US Saint-Malo | - | FC Versailles | 1:2 | ||||
| 29. Jornada | 21.05.2022 | Stade Plabennec | - | US Saint-Malo | 0:6 | |
|||
| 30. Jornada | 28.05.2022 | US Saint-Malo | - | St-Pryvé St-Hilaire | 1:0 |
Francia