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| 25.09.2021 | 17:00 | Saint-Étienne | - | Niza | 0:3 (0:1) | |
| 19:00 | RC Strasbourg | - | Lille | 1:2 (0:1) | ||
| 21:00 | Lyon | - | Lorient | 1:1 (0:1) | ||
| 21:00 | París Saint-Germain | - | Montpellier | 2:0 (1:0) | ||
| 26.09.2021 | 13:00 | Girondins de Burdeos | - | Rennes | 1:1 (0:0) | |
| 15:00 | Troyes | - | Angers | 1:1 (1:0) | ||
| 15:00 | Stade Brestois | - | FC Metz | 1:2 (0:1) | ||
| 15:00 | Stade de Reims | - | Nantes | 3:1 (0:0) | ||
| 17:00 | Clermont Foot 63 | - | Mónaco | 1:3 (1:1) | ||
| 20:45 | Marsella | - | RC Lens | 2:3 (2:2) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
París Saint-Germain | 8 | 8 | 0 | 0 | 22:7 | 15 | 24 |
| 2 |
|
Marsella | 8 | 4 | 3 | 1 | 15:9 | 6 | 15 |
| 3 |
|
RC Lens | 8 | 4 | 3 | 1 | 14:10 | 4 | 15 |
| 4 |
|
Niza | 8 | 4 | 3 | 1 | 16:4 | 12 | 14 |
| 5 |
|
Angers | 8 | 3 | 4 | 1 | 11:7 | 4 | 13 |
| 6 |
|
Lorient | 8 | 3 | 4 | 1 | 9:8 | 1 | 13 |
| 7 |
|
Lyon | 8 | 3 | 3 | 2 | 13:12 | 1 | 11 |
| 8 |
|
Mónaco | 8 | 3 | 2 | 3 | 11:11 | 0 | 11 |
| 9 |
|
Lille | 8 | 3 | 2 | 3 | 11:14 | -3 | 11 |
| 10 |
|
Nantes | 8 | 3 | 1 | 4 | 11:10 | 1 | 10 |
| 11 |
|
Stade de Reims | 8 | 2 | 4 | 2 | 10:9 | 1 | 10 |
| 12 |
|
RC Strasbourg | 8 | 3 | 1 | 4 | 12:13 | -1 | 10 |
| 13 |
|
Rennes | 8 | 2 | 3 | 3 | 10:9 | 1 | 9 |
| 14 |
|
Montpellier | 8 | 2 | 3 | 3 | 15:15 | 0 | 9 |
| 15 |
|
Clermont Foot 63 | 8 | 2 | 3 | 3 | 11:19 | -8 | 9 |
| 16 |
|
Girondins de Burdeos | 8 | 1 | 4 | 3 | 11:17 | -6 | 7 |
| 17 |
|
Troyes | 8 | 1 | 3 | 4 | 8:12 | -4 | 6 |
| 18 |
|
FC Metz | 8 | 1 | 3 | 4 | 9:16 | -7 | 6 |
| 19 |
|
Stade Brestois | 8 | 0 | 4 | 4 | 9:16 | -7 | 4 |
| 20 |
|
Saint-Étienne | 8 | 0 | 3 | 5 | 7:17 | -10 | 3 |
| Champions League | |
| CL Ronda previa | |
| Europa League | |
| ECL Ronda previa | |
| Permanencia | |
| Descenso |
