 |
 |
|
|
| 15.01.2022 | 19:00 | Pumas UNAM | - | CF América | 0:1 (0:1) | |
| 16.01.2022 | 00:00 | Gallos Blancos | - | CF Pachuca | 0:2 (0:0) | |
| 19:00 | Puebla FC | - | CF Monterrey | 0:3 (0:0) | ||
| 17.01.2022 | 19:00 | Atlas Guadalajara | - | Mazatlán FC | 1:1 (1:1) | |
| 18.01.2022 | 00:00 | Deportivo Toluca | - | Club Tijuana | 3:3 (1:2) | |
| 02:00 | UANL Tigres | - | Deportivo Guadalajara | 1:1 (0:0) | ||
| 04:00 | Club León | - | FC Juárez | 1:3 (0:2) | ||
| 19.01.2022 | 00:00 | Atlético San Luis | - | Cruz Azul | 1:1 (1:1) | |
| 20.01.2022 | 02:00 | Santos Laguna | - | Club Necaxa | 1:1 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Monterrey | 2 | 2 | 0 | 0 | 6:0 | 6 | 6 |
| 2 |
|
Deportivo Guadalajara | 2 | 1 | 1 | 0 | 5:2 | 3 | 4 |
| 3 |
|
Deportivo Toluca | 2 | 1 | 1 | 0 | 6:4 | 2 | 4 |
| 4 |
|
UANL Tigres | 2 | 1 | 1 | 0 | 4:2 | 2 | 4 |
| 5 |
|
Club Tijuana | 2 | 1 | 1 | 0 | 5:4 | 1 | 4 |
| 6 |
|
Cruz Azul | 2 | 1 | 1 | 0 | 3:2 | 1 | 4 |
| 7 |
|
Atlético San Luis | 2 | 1 | 1 | 0 | 2:1 | 1 | 4 |
|
CF América | 2 | 1 | 1 | 0 | 2:1 | 1 | 4 | |
| 9 |
|
FC Juárez | 2 | 1 | 0 | 1 | 3:2 | 1 | 3 |
| 10 |
|
Pumas UNAM | 2 | 1 | 0 | 1 | 1:1 | 0 | 3 |
| 11 |
|
CF Pachuca | 2 | 1 | 0 | 1 | 3:4 | -1 | 3 |
| 12 |
|
Atlas Guadalajara | 2 | 0 | 2 | 0 | 2:2 | 0 | 2 |
| 13 |
|
Mazatlán FC | 2 | 0 | 1 | 1 | 2:3 | -1 | 1 |
|
Santos Laguna | 2 | 0 | 1 | 1 | 2:3 | -1 | 1 | |
| 15 |
|
Club Necaxa | 2 | 0 | 1 | 1 | 2:4 | -2 | 1 |
| 16 |
|
Club León | 2 | 0 | 0 | 2 | 1:4 | -3 | 0 |
| 17 |
|
Puebla FC | 2 | 0 | 0 | 2 | 1:6 | -5 | 0 |
| 18 |
|
Gallos Blancos | 2 | 0 | 0 | 2 | 0:5 | -5 | 0 |
| Playoff |
