| Plantilla | Partidos jugados | ||
| Orden |
| Nombre |  |
 |
 |
 |
 |
 |
 |
 |
 |
| Diego López | 3420' | 38 | 38 | - | - | - | 3 | - | - |
| Capdevila | 3330' | 37 | 37 | - | - | 5 | 5 | - | 1 |
| Diego Godín | 3184' | 36 | 36 | - | 1 | 3 | 8 | - | 1 |
| Cani | 2195' | 35 | 27 | 8 | 19 | 2 | 5 | - | 1 |
| Giuseppe Rossi | 2332' | 34 | 27 | 7 | 13 | 10 | 3 | - | - |
| Bruno Soriano | 2796' | 33 | 31 | 2 | 4 | - | 9 | - | - |
| Nilmar | 2473' | 33 | 28 | 5 | 10 | 11 | 1 | - | - |
| Marcos Senna | 2198' | 30 | 26 | 4 | 9 | 1 | 6 | - | - |
| Llorente | 1769' | 29 | 20 | 9 | 11 | 9 | 8 | 1 | - |
| Robert Pirés | 1279' | 28 | 13 | 15 | 9 | 4 | 4 | - | - |
| Ángel | 1981' | 24 | 22 | 2 | 3 | 1 | 8 | 1 | - |
| Ariel Ibagaza | 1258' | 24 | 14 | 10 | 12 | 2 | 6 | - | - |
| Santi Cazorla | 1485' | 24 | 16 | 8 | 5 | 5 | 4 | - | - |
| David Fuster | 1119' | 22 | 11 | 11 | 9 | 3 | 6 | - | - |
| Gonzalo Rodríguez | 1673' | 21 | 19 | 2 | - | - | 2 | 1 | 2 |
| Javi Venta | 1413' | 18 | 16 | 2 | 1 | - | 4 | - | - |
| Marcano | 1317' | 16 | 15 | 1 | 2 | 1 | 4 | 1 | - |
| Sebastián Eguren | 852' | 14 | 9 | 5 | 1 | - | 4 | - | - |
| Damián Escudero | 345' | 13 | 3 | 10 | 3 | 1 | - | - | - |
| Mateo Musacchio | 402' | 7 | 5 | 2 | - | - | - | - | 1 |
| Jonathan Pereira | 127' | 6 | - | 6 | - | - | 2 | - | - |
| Marco Rubén | 118' | 4 | 1 | 3 | - | - | - | - | - |
| Kiko Olivas | 117' | 2 | 2 | - | - | - | - | - | 1 |
| Javier Matilla | 166' | 2 | 2 | - | 1 | - | - | - | - |
| Marcos Gullón | 4' | 1 | - | 1 | - | - | - | - | - |
| Joan Oriol | - | - | - | - | - | - | - | - | - |
| Oliva | - | - | - | - | - | - | - | - | - |
| Hernán Pérez | - | - | - | - | - | - | - | - | - |
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