| 1. Jornada | 29.08.2021 | UD SS Reyes | - | Extremadura UD | 1:0 | ||||
| 2. Jornada | 04.09.2021 | Extremadura UD | - | SD Logroñés | 0:0 | ||||
| 3. Jornada | 12.09.2021 | Unionistas CF | - | Extremadura UD | 3:0 | ||||
| 4. Jornada | 17.09.2021 | Extremadura UD | - | Racing de Ferrol | 1:0 | ||||
| 5. Jornada | 26.09.2021 | Extremadura UD | - | Rayo Majadahonda | 3:2 | ||||
| 6. Jornada | 03.10.2021 | CF Talavera | - | Extremadura UD | 1:1 | ||||
| 7. Jornada | 09.10.2021 | Extremadura UD | - | Valladolid B | 1:0 | ||||
| 8. Jornada | 16.10.2021 | CyD Leonesa | - | Extremadura UD | 2:1 | ||||
| 9. Jornada | 22.10.2021 | Extremadura UD | - | CD Tudelano | 1:1 | ||||
| 10. Jornada | 30.10.2021 | CD Badajoz | - | Extremadura UD | 2:0 |  |
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| 11. Jornada | 07.11.2021 | Extremadura UD | - | Inter de Madrid | 1:2 | ||||
| 18. Jornada | 08.01.2022 | Real Unión | - | Extremadura UD | 0:1 |
España
