| 4. Jornada | 14.08.2021 | CF Monterrey [Sub 18] | - | CF Pachuca [Sub 18] | 1:2 | ||||
| 6. Jornada | 22.08.2021 | Gallos Blancos [Sub 18] | - | CF Pachuca [Sub 18] | 1:0 | ||||
| 7. Jornada | 29.08.2021 | Cruz Azul [Sub 18] | - | CF Pachuca [Sub 18] | 1:0 | ||||
| 8. Jornada | 13.09.2021 | CF Pachuca [Sub 18] | - | Deportivo Toluca [Sub 18] | 2:2 | ||||
| 9. Jornada | 18.09.2021 | Deportivo Guadalajara [Sub 18] | - | CF Pachuca [Sub 18] | 0:4 | ||||
| 10. Jornada | 23.09.2021 | CF Pachuca [Sub 18] | - | Club Necaxa [Sub 18] | 5:1 | ||||
| 11. Jornada | 28.09.2021 | CF Pachuca [Sub 18] | - | CF América [Sub 18] | 4:1 | ||||
| 17. Jornada | 10.11.2021 | Club Tijuana [Sub 18] | - | CF Pachuca [Sub 18] | 2:2 |
México