| 2. Jornada | 03.09.2021 | CF Talavera | - | UD SS Reyes | 2:0 | ||||
| 3. Jornada | 12.09.2021 | UD SS Reyes | - | Rayo Majadahonda | 2:1 |  |
|||
| 6. Jornada | 02.10.2021 | UD Logroñés | - | UD SS Reyes | 1:0 | ||||
| 7. Jornada | 10.10.2021 | UD SS Reyes | - | Inter de Madrid | 1:0 | ||||
| 8. Jornada | 16.10.2021 | Deportivo | - | UD SS Reyes | 1:0 | ||||
| 9. Jornada | 24.10.2021 | UD SS Reyes | - | CD Badajoz | 0:0 | ||||
| 11. Jornada | 07.11.2021 | UD SS Reyes | - | Real Unión | 0:2 | |
|||
| 12. Jornada | 14.11.2021 | UD SS Reyes | - | Zamora CF | 3:1 | ||||
| 20. Jornada | 26.01.2022 | CD Badajoz | - | UD SS Reyes | 2:1 | ||||
| 23. Jornada | 13.02.2022 | UD SS Reyes | - | CF Talavera | 1:0 | ||||
| 24. Jornada | 20.02.2022 | Zamora CF | - | UD SS Reyes | 0:3 | ||||
| 25. Jornada | 27.02.2022 | UD SS Reyes | - | Deportivo | 0:0 | |
|||
| 26. Jornada | 05.03.2022 | SD Logroñés | - | UD SS Reyes | 1:0 | ||||
| 27. Jornada | 12.03.2022 | UD SS Reyes | - | CD Calahorra | 0:3 | ||||
| 28. Jornada | 19.03.2022 | Real Unión | - | UD SS Reyes | 0:1 | ||||
| 29. Jornada | 27.03.2022 | Racing de Ferrol | - | UD SS Reyes | 1:0 | |
|||
| 32. Jornada | 17.04.2022 | UD SS Reyes | - | CyD Leonesa | 0:3 | ||||
| 33. Jornada | 24.04.2022 | Inter de Madrid | - | UD SS Reyes | 0:0 | |
España