| 3. Jornada | 27.08.2021 | Las Palmas | - | Huesca | 2:1 | ||||
| 4. Jornada | 06.09.2021 | Huesca | - | Real Oviedo | 1:2 | ||||
| 5. Jornada | 13.09.2021 | Lugo | - | Huesca | 3:2 | ||||
| 6. Jornada | 19.09.2021 | Huesca | - | CF Fuenlabrada | 0:0 | ||||
| 7. Jornada | 24.09.2021 | Real Sociedad B | - | Huesca | 0:2 | ||||
| 8. Jornada | 02.10.2021 | Huesca | - | Tenerife | 1:2 | ||||
| 11. Jornada | 19.10.2021 | Huesca | - | Málaga | 0:0 | ||||
| 12. Jornada | 24.10.2021 | Burgos CF | - | Huesca | 3:1 | ||||
| 13. Jornada | 30.10.2021 | Huesca | - | SD Amorebieta | 1:1 | ||||
| 15. Jornada | 05.11.2021 | Huesca | - | Leganés | 0:2 | ||||
| 16. Jornada | 13.11.2021 | Mirandés | - | Huesca | 0:1 | ||||
| 18. Jornada | 27.11.2021 | Almería | - | Huesca | 0:0 | ||||
| 22. Jornada | 02.01.2022 | Huesca | - | Girona | 0:1 | ||||
| 23. Jornada | 08.01.2022 | FC Cartagena | - | Huesca | 0:3 |  |
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| 24. Jornada | 23.01.2022 | Huesca | - | Ponferradina | 1:2 | ||||
| 29. Jornada | 26.02.2022 | UD Ibiza | - | Huesca | 2:1 | ||||
| 33. Jornada | 27.03.2022 | Málaga | - | Huesca | 0:2 | ||||
| 41. Jornada | 21.05.2022 | Huesca | - | Real Sociedad B | 3:2 |  |
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| 42. Jornada | 29.05.2022 | Valladolid | - | Huesca | 3:0 |
España