| 1. Jornada | 08.08.2021 | FC Metz | - | Lille | 3:3 |  |
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| 2. Jornada | 15.08.2021 | Nantes | - | FC Metz | 2:0 | ||||
| 3. Jornada | 22.08.2021 | FC Metz | - | Stade de Reims | 1:1 | ||||
| 4. Jornada | 29.08.2021 | Clermont Foot 63 | - | FC Metz | 2:2 | ||||
| 5. Jornada | 12.09.2021 | FC Metz | - | Troyes | 0:2 | ||||
| 6. Jornada | 17.09.2021 | RC Strasbourg | - | FC Metz | 3:0 | ||||
| 7. Jornada | 22.09.2021 | FC Metz | - | París Saint-Germain | 1:2 | ||||
| 8. Jornada | 26.09.2021 | Stade Brestois 29 | - | FC Metz | 1:2 | ||||
| 9. Jornada | 03.10.2021 | Angers | - | FC Metz | 3:2 | ||||
| 10. Jornada | 17.10.2021 | FC Metz | - | Rennes | 0:3 | ||||
| 11. Jornada | 24.10.2021 | RC Lens | - | FC Metz | 4:1 | ||||
| 13. Jornada | 07.11.2021 | Marsella | - | FC Metz | 0:0 |
Francia
Guadalupe