| 1. Jornada | 25.07.2021 | Club Tijuana [Sub 18] | - | UANL Tigres [Sub 18] | 1:0 | ||||
| 2. Jornada | 01.08.2021 | Deportivo Toluca [Sub 18] | - | UANL Tigres [Sub 18] | 4:0 | ||||
| 3. Jornada | 07.08.2021 | UANL Tigres [Sub 18] | - | Santos Laguna [Sub 18] | 0:0 | ||||
| 4. Jornada | 13.08.2021 | Puebla FC [Sub 18] | - | UANL Tigres [Sub 18] | 1:2 | ||||
| 5. Jornada | 17.08.2021 | UANL Tigres [Sub 18] | - | Gallos Blancos [Sub 18] | 1:0 |  |
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| 7. Jornada | 28.08.2021 | UANL Tigres [Sub 18] | - | Atlas Guadalajara [Sub 18] | 0:0 | ||||
| 8. Jornada | 11.09.2021 | UANL Tigres [Sub 18] | - | Club León [Sub 18] | 1:1 | ||||
| 10. Jornada | 25.09.2021 | UANL Tigres [Sub 18] | - | Pumas UNAM [Sub 18] | 6:0 | ||||
| 14. Jornada | 20.10.2021 | UANL Tigres [Sub 18] | - | CF Pachuca [Sub 18] | 3:2 |
México