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| 25.02.2023 | 17:00 | Sevilla Atlético | - | Cádiz CF B | 1:0 (1:0) | |
| 17:00 | Juventud Torremolinos | - | CD San Roque | 0:1 (0:1) | ||
| 26.02.2023 | 12:00 | Utrera CD | - | UCAM Murcia CF | 1:1 (0:0) | |
| 12:00 | FC Cartagena B | - | Granada B | 1:1 (0:1) | ||
| 12:00 | Atlético Mancha Real | - | Yeclano Deportivo | 1:2 (1:1) | ||
| 12:00 | Mar Menor CF | - | CD El Ejido 2012 | 0:1 (0:0) | ||
| 12:00 | Vélez CF | - | Betis B | 2:4 (1:2) | ||
| 12:00 | Xerez DFC | - | Atlético Sanluqueño CF | 3:2 (0:2) | ||
| 12:30 | RC Recreativo | - | Antequera CF | 0:2 (0:2) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Antequera CF | 23 | 18 | 4 | 1 | 46:15 | 31 | 58 |
| 2 |
|
RC Recreativo | 23 | 11 | 7 | 5 | 26:19 | 7 | 40 |
| 3 |
|
Yeclano Deportivo | 23 | 10 | 8 | 5 | 24:18 | 6 | 38 |
| 4 |
|
UCAM Murcia CF | 23 | 9 | 9 | 5 | 33:22 | 11 | 36 |
| 5 |
|
Granada B | 23 | 10 | 6 | 7 | 32:24 | 8 | 36 |
| 6 |
|
Atlético Sanluqueño CF | 23 | 9 | 7 | 7 | 29:25 | 4 | 34 |
| 7 |
|
CD San Roque | 23 | 9 | 6 | 8 | 25:21 | 4 | 33 |
| 8 |
|
Betis B | 23 | 8 | 8 | 7 | 21:21 | 0 | 32 |
| 9 |
|
Mar Menor CF | 23 | 8 | 8 | 7 | 24:22 | 2 | 32 |
| 10 |
|
Vélez CF | 23 | 9 | 3 | 11 | 24:32 | -8 | 30 |
| 11 |
|
FC Cartagena B | 23 | 8 | 5 | 10 | 23:29 | -6 | 29 |
| 12 |
|
CD El Ejido 2012 | 23 | 8 | 4 | 11 | 25:27 | -2 | 28 |
| 13 |
|
Atlético Mancha Real | 23 | 7 | 5 | 11 | 17:30 | -13 | 26 |
| 14 |
|
Xerez DFC | 23 | 6 | 7 | 10 | 20:25 | -5 | 25 |
| 15 |
|
Cádiz CF B | 23 | 6 | 7 | 10 | 23:30 | -7 | 25 |
| 16 |
|
Juventud Torremolinos | 23 | 5 | 9 | 9 | 19:22 | -3 | 24 |
| 17 |
|
Sevilla Atlético | 23 | 6 | 3 | 14 | 20:26 | -6 | 21 |
| 18 |
|
Utrera CD | 23 | 5 | 4 | 14 | 18:41 | -23 | 19 |
| Ascenso | |
| Playoff | |
| Descenso |
