| 1. Jornada | 29.08.2021 | CD Badajoz | - | CF Talavera | 2:0 | ||||
| 2. Jornada | 03.09.2021 | CF Talavera | - | UD SS Reyes | 2:0 |  |
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| 3. Jornada | 11.09.2021 | Real Racing | - | CF Talavera | 5:1 | ||||
| 4. Jornada | 19.09.2021 | CF Talavera | - | CD Calahorra | 0:0 | ||||
| 5. Jornada | 26.09.2021 | SD Logroñés | - | CF Talavera | 3:2 | ||||
| 6. Jornada | 03.10.2021 | CF Talavera | - | Extremadura UD | 1:1 | ||||
| 9. Jornada | 23.10.2021 | UD Logroñés | - | CF Talavera | 1:0 |  |
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| 10. Jornada | 29.10.2021 | CF Talavera | - | Valladolid B | 0:2 | ||||
| 11. Jornada | 06.11.2021 | CD Tudelano | - | CF Talavera | 0:2 | ||||
| 12. Jornada | 14.11.2021 | CF Talavera | - | Racing de Ferrol | 1:2 | ||||
| 13. Jornada | 21.11.2021 | Bilbao Athletic | - | CF Talavera | 0:1 | |
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| 14. Jornada | 28.11.2021 | CF Talavera | - | Rayo Majadahonda | 0:0 | ||||
| 33. Jornada | 24.04.2022 | CF Talavera | - | Deportivo | 1:1 | ||||
| 35. Jornada | 08.05.2022 | CF Talavera | - | SD Logroñés | 1:0 | |
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| 36. Jornada | 14.05.2022 | Real Unión | - | CF Talavera | 3:1 | ||||
| 37. Jornada | 21.05.2022 | CF Talavera | - | CyD Leonesa | 0:5 | ||||
| 38. Jornada | 28.05.2022 | CD Calahorra | - | CF Talavera | 1:2 | |
Nigeria