| 1. Jornada | 08.01.2022 | FC Juárez | - | Club Necaxa | 2:1 | ||||
| 2. Jornada | 16.01.2022 | Cruz Azul | - | FC Juárez | 1:0 | ||||
| 3. Jornada | 21.01.2022 | Atlético San Luis | - | FC Juárez | 0:1 | ||||
| 4. Jornada | 10.02.2022 | FC Juárez | - | Deportivo Guadalajara | 1:3 | ||||
| 6. Jornada | 19.02.2022 | FC Juárez | - | Santos Laguna | 0:0 | ||||
| 7. Jornada | 26.02.2022 | FC Juárez | - | UANL Tigres | 2:3 |  |
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| 8. Jornada | 02.03.2022 | Puebla FC | - | FC Juárez | 1:1 | ||||
| 9. Jornada | 05.03.2022 | FC Juárez | - | Club León | 0:1 | ||||
| 10. Jornada | 12.03.2022 | FC Juárez | - | Atlas Guadalajara | 1:2 | ||||
| 11. Jornada | 21.03.2022 | Club Tijuana | - | FC Juárez | 1:0 | ||||
| 12. Jornada | 03.04.2022 | FC Juárez | - | Pumas UNAM | 0:1 | ||||
| 13. Jornada | 10.04.2022 | CF América | - | FC Juárez | 3:0 |  |
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| 15. Jornada | 20.04.2022 | Deportivo Toluca | - | FC Juárez | 0:1 | ||||
| 16. Jornada | 23.04.2022 | FC Juárez | - | Mazatlán FC | 0:2 | ||||
| 17. Jornada | 01.05.2022 | Gallos Blancos | - | FC Juárez | 4:0 |
España
