| 1. Jornada | 12.02.2022 | Almagro | - | Mitre de SdE | 2:1 | ||||
| 2. Jornada | 19.02.2022 | Sacachispas | - | Almagro | 0:1 | ||||
| 3. Jornada | 28.02.2022 | Almagro | - | Instituto de Córdoba | 0:1 | ||||
| 4. Jornada | 05.03.2022 | Agropecuario Argentino | - | Almagro | 2:2 |  |
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| 5. Jornada | 11.03.2022 | Almagro | - | Tristan Suárez | 1:0 | ||||
| 8. Jornada | 28.03.2022 | Brown de Adrogué | - | Almagro | 3:0 | ||||
| 10. Jornada | 10.04.2022 | Guillermo Brown | - | Almagro | 0:1 | ||||
| 11. Jornada | 17.04.2022 | Almagro | - | Atlético Rafaela | 3:1 | |
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| 12. Jornada | 24.04.2022 | Ramón Santamarina | - | Almagro | 0:0 | ||||
| 13. Jornada | 30.04.2022 | Almagro | - | Estudiantes de Caseros | 1:1 | ||||
| 14. Jornada | 07.05.2022 | Atlanta | - | Almagro | 1:1 | ||||
| 15. Jornada | 14.05.2022 | Almagro | - | San Martín de San Juan | 1:0 | ||||
| 16. Jornada | 24.05.2022 | Chaco For Ever | - | Almagro | 0:1 | ||||
| 17. Jornada | 30.05.2022 | Almagro | - | San Telmo | 2:1 | ||||
| 18. Jornada | 05.06.2022 | Gimnasia de Mendoza | - | Almagro | 1:0 | |
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| 23. Jornada | 09.07.2022 | Almagro | - | Villa Dálmine | 1:0 | ||||
| 34. Jornada | 19.09.2022 | Almagro | - | Deportivo Maipú | 1:0 |
Argentina