| 1. Jornada | 18.07.2021 | Huracán | - | Defensa y Justicia | 2:1 |  |
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| 2. Jornada | 24.07.2021 | Atlético Tucumán | - | Huracán | 1:0 | ||||
| 3. Jornada | 27.07.2021 | Huracán | - | Colón de Santa Fe | 1:1 |  |
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| 4. Jornada | 01.08.2021 | River Plate | - | Huracán | 1:1 | |
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| 5. Jornada | 07.08.2021 | Huracán | - | CA Lanús | 0:1 | ||||
| 6. Jornada | 14.08.2021 | Huracán | - | Unión de Santa Fe | 0:0 | ||||
| 13. Jornada | 28.09.2021 | Newell's Old Boys | - | Huracán | 0:1 | ||||
| 14. Jornada | 02.10.2021 | Huracán | - | Arsenal de Sarandí | 1:0 | ||||
| 15. Jornada | 08.10.2021 | Central Córdoba SdE | - | Huracán | 1:2 | ||||
| 16. Jornada | 17.10.2021 | Huracán | - | Boca Juniors | 0:3 | ||||
| 17. Jornada | 21.10.2021 | Banfield | - | Huracán | 1:4 | |
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| 18. Jornada | 24.10.2021 | Huracán | - | San Lorenzo | 2:1 | ||||
| 19. Jornada | 30.10.2021 | Talleres de Córdoba | - | Huracán | 1:0 | ||||
| 20. Jornada | 08.11.2021 | Huracán | - | Argentinos Juniors | 1:1 | |
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| 21. Jornada | 19.11.2021 | Estudiantes | - | Huracán | 4:1 | ||||
| 22. Jornada | 23.11.2021 | Huracán | - | Patronato de Paraná | 1:0 | ||||
| 23. Jornada | 30.11.2021 | Platense | - | Huracán | 4:2 | ||||
| 24. Jornada | 05.12.2021 | Huracán | - | Racing Club | 1:0 | |
Argentina
