| 9. Jornada | 17.10.2021 | Rayo | - | Elche | 2:1 |  |
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| 10. Jornada | 24.10.2021 | Betis | - | Rayo | 3:2 | ||||
| 28. Jornada | 13.03.2022 | Rayo | - | Sevilla | 1:1 | ||||
| 30. Jornada | 03.04.2022 | Granada | - | Rayo | 2:2 |  |
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| 32. Jornada | 16.04.2022 | Alavés | - | Rayo | 1:0 | ||||
| 33. Jornada | 21.04.2022 | Espanyol | - | Rayo | 0:1 | |
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| 21. Jornada | 24.04.2022 | Barcelona | - | Rayo | 0:1 | |
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| 34. Jornada | 01.05.2022 | Rayo | - | Real Sociedad | 1:1 | ||||
| 37. Jornada | 15.05.2022 | Mallorca | - | Rayo | 2:1 |
España