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| 12.08.2022 | 00:00 | Godoy Cruz | - | Aldosivi | 2:0 (1:0) | |
| 02:30 | Atlético Tucumán | - | Central Córdoba SdE | 1:0 (0:0) | ||
| 02:30 | Colón de Santa Fe | - | Arsenal de Sarandí | 1:1 (1:0) | ||
| 13.08.2022 | 00:00 | Huracán | - | Sarmiento de Junín | 4:1 (2:1) | |
| 00:00 | Platense | - | Banfield | 3:1 (0:1) | ||
| 02:30 | Patronato de Paraná | - | San Lorenzo | 3:2 (1:1) | ||
| 20:30 | Defensa y Justicia | - | Tigre | 0:0 (0:0) | ||
| 20:30 | Rosario Central | - | Barracas Central | 3:1 (1:1) | ||
| 23:00 | CA Lanús | - | Independiente | 1:1 (1:0) | ||
| 14.08.2022 | 01:30 | River Plate | - | Newell's Old Boys | 4:1 (2:0) | |
| 20:30 | Vélez Sarsfield | - | Gimnasia de La Plata | 1:1 (0:0) | ||
| 23:00 | Argentinos Juniors | - | Unión de Santa Fe | 2:0 (1:0) | ||
| 23:00 | Estudiantes | - | Talleres de Córdoba | 1:0 (0:0) | ||
| 15.08.2022 | 01:30 | Racing Club | - | Boca Juniors | 0:0 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Atlético Tucumán | 13 | 8 | 4 | 1 | 14:6 | 8 | 28 |
| 2 |
|
Gimnasia de La Plata | 13 | 7 | 4 | 2 | 14:7 | 7 | 25 |
| 3 |
|
Huracán | 13 | 6 | 5 | 2 | 16:10 | 6 | 23 |
| 4 |
|
Argentinos Juniors | 13 | 7 | 2 | 4 | 17:12 | 5 | 23 |
| 5 |
|
Unión de Santa Fe | 13 | 6 | 4 | 3 | 22:21 | 1 | 22 |
| 6 |
|
River Plate | 13 | 6 | 3 | 4 | 21:13 | 8 | 21 |
| 7 |
|
Racing Club | 13 | 5 | 6 | 2 | 19:11 | 8 | 21 |
| 8 |
|
Patronato de Paraná | 13 | 6 | 3 | 4 | 19:15 | 4 | 21 |
| 9 |
|
Godoy Cruz | 13 | 6 | 3 | 4 | 15:11 | 4 | 21 |
|
Platense | 13 | 5 | 6 | 2 | 15:11 | 4 | 21 | |
| 11 |
|
Boca Juniors | 13 | 6 | 1 | 6 | 18:20 | -2 | 19 |
| 12 |
|
Tigre | 13 | 4 | 5 | 4 | 20:18 | 2 | 17 |
| 13 |
|
San Lorenzo | 13 | 3 | 8 | 2 | 17:15 | 2 | 17 |
| 14 |
|
Arsenal de Sarandí | 13 | 3 | 8 | 2 | 15:15 | 0 | 17 |
| 15 |
|
Newell's Old Boys | 13 | 4 | 5 | 4 | 11:13 | -2 | 17 |
| 16 |
|
Sarmiento de Junín | 13 | 5 | 2 | 6 | 14:17 | -3 | 17 |
| 17 |
|
Rosario Central | 13 | 5 | 2 | 6 | 11:14 | -3 | 17 |
| 18 |
|
Estudiantes | 13 | 4 | 4 | 5 | 14:16 | -2 | 16 |
| 19 |
|
Banfield | 13 | 3 | 6 | 4 | 13:13 | 0 | 15 |
| 20 |
|
Colón de Santa Fe | 13 | 3 | 6 | 4 | 11:13 | -2 | 15 |
|
Defensa y Justicia | 13 | 3 | 6 | 4 | 11:13 | -2 | 15 | |
| 22 |
|
Central Córdoba SdE | 13 | 4 | 2 | 7 | 14:18 | -4 | 14 |
| 23 |
|
Barracas Central | 13 | 3 | 5 | 5 | 14:19 | -5 | 14 |
| 24 |
|
Talleres de Córdoba | 13 | 3 | 4 | 6 | 10:13 | -3 | 13 |
| 25 |
|
Independiente | 13 | 3 | 3 | 7 | 12:16 | -4 | 12 |
| 26 |
|
Vélez Sarsfield | 13 | 1 | 7 | 5 | 13:17 | -4 | 10 |
| 27 |
|
Aldosivi | 13 | 2 | 2 | 9 | 7:21 | -14 | 8 |
| 28 |
|
CA Lanús | 13 | 1 | 4 | 8 | 11:20 | -9 | 7 |
