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| 06.12.2008 | 20:00 | Villarreal | - | Getafe | 3:3 (0:3) | |
| 20:00 | Sporting | - | Atlético | 2:5 (1:2) | ||
| 22:00 | Barcelona | - | Valencia | 4:0 (2:0) | ||
| 07.12.2008 | 17:00 | Mallorca | - | RC Recreativo | 2:3 (2:2) | |
| 17:00 | Osasuna | - | Valladolid | 3:3 (2:0) | ||
| 17:00 | Deportivo | - | Málaga | 2:0 (0:0) | ||
| 17:00 | Numancia | - | Almería | 2:1 (1:1) | ||
| 17:00 | Real Racing | - | Athletic | 1:1 (0:0) | ||
| 19:00 | Betis | - | Espanyol | 1:1 (0:0) | ||
| 21:00 | Real Madrid | - | Sevilla | 3:4 (1:3) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta | 1.ª parte | 2.ª parte |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Barcelona | 14 | 11 | 2 | 1 | 44:9 | 35 | 35 |
| 2 |
|
Villarreal | 14 | 8 | 5 | 1 | 26:18 | 8 | 29 |
| 3 |
|
Valencia | 14 | 8 | 3 | 3 | 28:18 | 10 | 27 |
| 4 |
|
Sevilla | 14 | 8 | 3 | 3 | 22:14 | 8 | 27 |
| 5 |
|
Real Madrid | 14 | 8 | 2 | 4 | 33:24 | 9 | 26 |
| 6 |
|
Atlético | 14 | 7 | 3 | 4 | 33:21 | 12 | 24 |
| 7 |
|
Deportivo | 14 | 7 | 3 | 4 | 16:14 | 2 | 24 |
| 8 |
|
Valladolid | 14 | 6 | 2 | 6 | 19:20 | -1 | 20 |
| 9 |
|
Betis | 14 | 5 | 3 | 6 | 21:19 | 2 | 18 |
| 10 |
|
Getafe | 14 | 4 | 6 | 4 | 17:19 | -2 | 18 |
| 11 |
|
Málaga | 14 | 5 | 3 | 6 | 21:25 | -4 | 18 |
| 12 |
|
Sporting | 14 | 6 | 0 | 8 | 23:32 | -9 | 18 |
| 13 |
|
Real Racing | 14 | 4 | 4 | 6 | 16:20 | -4 | 16 |
| 14 |
|
Almería | 14 | 4 | 3 | 7 | 15:23 | -8 | 15 |
| 15 |
|
Numancia | 14 | 4 | 2 | 8 | 17:28 | -11 | 14 |
| 16 |
|
Athletic | 14 | 3 | 4 | 7 | 16:24 | -8 | 13 |
| 17 |
|
Mallorca | 14 | 3 | 4 | 7 | 16:25 | -9 | 13 |
| 18 |
|
Espanyol | 14 | 3 | 4 | 7 | 11:20 | -9 | 13 |
| 19 |
|
RC Recreativo | 14 | 2 | 4 | 8 | 9:22 | -13 | 10 |
| 20 |
|
Osasuna | 14 | 1 | 6 | 7 | 11:19 | -8 | 9 |
| Champions League | |
| CL Ronda previa | |
| Europa League | |
| Descenso |
