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| 20.12.2008 | 20:00 | Real Madrid | - | Valencia | 1:0 (1:0) | |
| 22:00 | Espanyol | - | Atlético | 2:3 (0:1) | ||
| 21.12.2008 | 17:00 | Mallorca | - | Sevilla | 0:0 (0:0) | |
| 17:00 | Osasuna | - | Getafe | 5:2 (4:0) | ||
| 17:00 | Deportivo | - | RC Recreativo | 4:1 (3:1) | ||
| 17:00 | Numancia | - | Valladolid | 4:3 (1:1) | ||
| 17:00 | Real Racing | - | Málaga | 1:1 (0:1) | ||
| 17:00 | Sporting | - | Almería | 1:0 (1:0) | ||
| 19:00 | Villarreal | - | Barcelona | 1:2 (0:0) | ||
| 21:00 | Betis | - | Athletic | 0:1 (0:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta | 1.ª parte | 2.ª parte |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Barcelona | 16 | 13 | 2 | 1 | 48:10 | 38 | 41 |
| 2 |
|
Sevilla | 16 | 9 | 4 | 3 | 23:14 | 9 | 31 |
| 3 |
|
Atlético | 16 | 9 | 3 | 4 | 38:23 | 15 | 30 |
| 4 |
|
Valencia | 16 | 9 | 3 | 4 | 30:20 | 10 | 30 |
| 5 |
|
Real Madrid | 16 | 9 | 2 | 5 | 34:26 | 8 | 29 |
| 6 |
|
Villarreal | 16 | 8 | 5 | 3 | 27:21 | 6 | 29 |
| 7 |
|
Deportivo | 16 | 8 | 3 | 5 | 20:18 | 2 | 27 |
| 8 |
|
Valladolid | 16 | 7 | 2 | 7 | 25:24 | 1 | 23 |
| 9 |
|
Málaga | 16 | 6 | 4 | 6 | 24:26 | -2 | 22 |
| 10 |
|
Getafe | 16 | 5 | 6 | 5 | 23:25 | -2 | 21 |
| 11 |
|
Sporting | 16 | 7 | 0 | 9 | 24:35 | -11 | 21 |
| 12 |
|
Athletic | 16 | 5 | 4 | 7 | 20:24 | -4 | 19 |
| 13 |
|
Betis | 16 | 5 | 3 | 8 | 21:22 | -1 | 18 |
| 14 |
|
Real Racing | 16 | 4 | 6 | 6 | 18:22 | -4 | 18 |
| 15 |
|
Numancia | 16 | 5 | 2 | 9 | 21:33 | -12 | 17 |
| 16 |
|
Almería | 16 | 4 | 4 | 8 | 16:25 | -9 | 16 |
| 17 |
|
Mallorca | 16 | 3 | 5 | 8 | 17:29 | -12 | 14 |
| 18 |
|
Espanyol | 16 | 3 | 4 | 9 | 14:25 | -11 | 13 |
| 19 |
|
RC Recreativo | 16 | 3 | 4 | 9 | 11:26 | -15 | 13 |
| 20 |
|
Osasuna | 16 | 2 | 6 | 8 | 16:22 | -6 | 12 |
| Champions League | |
| CL Ronda previa | |
| Europa League | |
| Descenso |
