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| 04.05.2010 | 20:00 | Getafe | - | Sporting | 1:1 (0:1) | |
| 20:00 | Barcelona | - | Tenerife | 4:1 (1:1) | ||
| 20:00 | Almería | - | Villarreal | 4:2 (3:0) | ||
| 22:00 | Valencia | - | Xerez CD | 3:1 (1:1) | ||
| 05.05.2010 | 20:00 | Atlético | - | Valladolid | 3:1 (1:0) | |
| 20:00 | Real Racing | - | Sevilla | 1:5 (0:2) | ||
| 20:00 | Zaragoza | - | Espanyol | 1:0 (0:0) | ||
| 20:00 | Osasuna | - | Deportivo | 3:1 (3:1) | ||
| 20:00 | Athletic | - | Málaga | 1:1 (1:1) | ||
| 22:00 | Mallorca | - | Real Madrid | 1:4 (1:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta | 1.ª parte | 2.ª parte |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Barcelona | 36 | 29 | 6 | 1 | 91:22 | 69 | 93 |
| 2 |
|
Real Madrid | 36 | 30 | 2 | 4 | 96:33 | 63 | 92 |
| 3 |
|
Valencia | 36 | 20 | 8 | 8 | 58:38 | 20 | 68 |
| 4 |
|
Sevilla | 36 | 18 | 6 | 12 | 60:44 | 16 | 60 |
| 5 |
|
Mallorca | 36 | 17 | 8 | 11 | 57:43 | 14 | 59 |
| 6 |
|
Getafe | 36 | 15 | 7 | 14 | 53:47 | 6 | 52 |
| 7 |
|
Villarreal | 36 | 15 | 7 | 14 | 53:54 | -1 | 52 |
| 8 |
|
Athletic | 36 | 14 | 9 | 13 | 47:48 | -1 | 51 |
| 9 |
|
Atlético | 36 | 13 | 7 | 16 | 56:57 | -1 | 46 |
| 10 |
|
Deportivo | 36 | 12 | 8 | 16 | 34:47 | -13 | 44 |
| 11 |
|
Osasuna | 36 | 11 | 9 | 16 | 35:43 | -8 | 42 |
| 12 |
|
Almería | 36 | 10 | 11 | 15 | 39:50 | -11 | 41 |
| 13 |
|
Espanyol | 36 | 10 | 11 | 15 | 27:43 | -16 | 41 |
| 14 |
|
Zaragoza | 36 | 10 | 10 | 16 | 41:58 | -17 | 40 |
| 15 |
|
Sporting | 36 | 9 | 12 | 15 | 35:48 | -13 | 39 |
| 16 |
|
Málaga | 36 | 7 | 15 | 14 | 40:45 | -5 | 36 |
| 17 |
|
Real Racing | 36 | 8 | 12 | 16 | 39:57 | -18 | 36 |
| 18 |
|
Tenerife | 36 | 9 | 8 | 19 | 38:71 | -33 | 35 |
| 19 |
|
Valladolid | 36 | 6 | 15 | 15 | 35:57 | -22 | 33 |
| 20 |
|
Xerez CD | 36 | 7 | 9 | 20 | 34:63 | -29 | 30 |
| Champions League | |
| CL Ronda previa | |
| Europa League | |
| Descenso |
