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| 27.10.2018 | 13:00 | FK Ural | - | FK Ufa | 1:1 (0:1) | |
| 15:30 | Arsenal Tula | - | FK Orenburg | 2:2 (1:0) | ||
| 18:00 | FK Rostov | - | Anzhi Makhachkala | 1:0 (1:0) | ||
| 28.10.2018 | 12:00 | Enisey Krasnoyarsk | - | Lokomotiv Moskva | 0:3 (0:1) | |
| 14:30 | Akhmat Grozny | - | Dinamo Moskva | 0:0 (0:0) | ||
| 17:00 | CSKA Moscú | - | FK Krasnodar | 1:2 (0:0) | ||
| 29.10.2018 | 16:00 | Krylia Sovetov | - | Zenit | 0:1 (0:1) | |
| 18:30 | Rubin Kazan | - | Spartak Moskva | 1:1 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Zenit | 12 | 9 | 1 | 2 | 21:9 | 12 | 28 |
| 2 |
|
FK Krasnodar | 12 | 7 | 1 | 4 | 20:10 | 10 | 22 |
| 3 |
|
FK Rostov | 12 | 6 | 3 | 3 | 12:6 | 6 | 21 |
| 4 |
|
Lokomotiv Moskva | 12 | 6 | 3 | 3 | 16:11 | 5 | 21 |
| 5 |
|
CSKA Moscú | 12 | 5 | 4 | 3 | 17:7 | 10 | 19 |
| 6 |
|
Rubin Kazan | 12 | 4 | 7 | 1 | 13:10 | 3 | 19 |
| 7 |
|
Spartak Moskva | 12 | 5 | 4 | 3 | 13:11 | 2 | 19 |
| 8 |
|
FK Orenburg | 12 | 4 | 4 | 4 | 13:11 | 2 | 16 |
| 9 |
|
Akhmat Grozny | 12 | 4 | 4 | 4 | 10:12 | -2 | 16 |
| 10 |
|
Arsenal Tula | 12 | 3 | 5 | 4 | 16:15 | 1 | 14 |
| 11 |
|
Dinamo Moskva | 12 | 3 | 5 | 4 | 10:10 | 0 | 14 |
| 12 |
|
FK Ural | 12 | 3 | 4 | 5 | 12:19 | -7 | 13 |
| 13 |
|
FK Ufa | 12 | 2 | 5 | 5 | 8:14 | -6 | 11 |
| 14 |
|
Krylia Sovetov | 12 | 3 | 2 | 7 | 5:16 | -11 | 11 |
| 15 |
|
Anzhi Makhachkala | 12 | 3 | 1 | 8 | 6:18 | -12 | 10 |
| 16 |
|
Enisey Krasnoyarsk | 12 | 1 | 3 | 8 | 6:19 | -13 | 6 |
| Champions League | |
| CL Ronda previa | |
| Europa League | |
| EL Ronda previa | |
| Permanencia | |
| Descenso |
