| 5. Jornada | 18.08.2021 | Cruz Azul [Sub 20] | - | CF Monterrey [Sub 20] | 2:1 | ||||
| 6. Jornada | 21.08.2021 | CF Monterrey [Sub 20] | - | Deportivo Guadalajara [Sub 20] | 1:1 |  |
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| 7. Jornada | 28.08.2021 | Club Tijuana [Sub 20] | - | CF Monterrey [Sub 20] | 1:0 | ||||
| 8. Jornada | 11.09.2021 | Atlas Guadalajara [Sub 20] | - | CF Monterrey [Sub 20] | 3:1 | ||||
| 9. Jornada | 19.09.2021 | CF Monterrey [Sub 20] | - | UANL Tigres [Sub 20] | 0:1 | ||||
| 11. Jornada | 22.09.2021 | CF Monterrey [Sub 20] | - | Deportivo Toluca [Sub 20] | 1:0 | ||||
| 10. Jornada | 26.09.2021 | Santos Laguna [Sub 20] | - | CF Monterrey [Sub 20] | 4:1 | ||||
| 12. Jornada | 01.10.2021 | FC Juárez [Sub 20] | - | CF Monterrey [Sub 20] | 1:0 | ||||
| 13. Jornada | 16.10.2021 | CF Monterrey [Sub 20] | - | Club León [Sub 20] | 1:1 | |
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| 14. Jornada | 19.10.2021 | Gallos Blancos [Sub 20] | - | CF Monterrey [Sub 20] | 1:1 | ||||
| 15. Jornada | 23.10.2021 | CF Monterrey [Sub 20] | - | Club Necaxa [Sub 20] | 5:1 | |
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| 16. Jornada | 31.10.2021 | Atlético San Luis [Sub 20] | - | CF Monterrey [Sub 20] | 3:1 | ||||
| 17. Jornada | 06.11.2021 | CF América [Sub 20] | - | CF Monterrey [Sub 20] | 2:0 |
México