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| 27.09.2008 | 20:00 | Betis | - | Real Madrid | 1:2 (0:1) | |
| 20:00 | Sporting | - | Villarreal | 0:1 (0:0) | ||
| 22:00 | Espanyol | - | Barcelona | 1:2 (1:0) | ||
| 28.09.2008 | 17:00 | Málaga | - | Valladolid | 2:1 (1:0) | |
| 17:00 | Almería | - | RC Recreativo | 1:0 (0:0) | ||
| 17:00 | Athletic | - | Getafe | 0:1 (0:0) | ||
| 17:00 | Real Racing | - | Mallorca | 1:2 (1:1) | ||
| 17:00 | Numancia | - | Osasuna | 0:0 (0:0) | ||
| 19:00 | Valencia | - | Deportivo | 4:2 (1:1) | ||
| 21:00 | Atlético | - | Sevilla | 0:1 (0:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta | 1.ª parte | 2.ª parte |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Valencia | 5 | 4 | 1 | 0 | 12:4 | 8 | 13 |
| 2 |
|
Villarreal | 5 | 4 | 1 | 0 | 7:2 | 5 | 13 |
| 3 |
|
Real Madrid | 5 | 4 | 0 | 1 | 16:7 | 9 | 12 |
| 4 |
|
Sevilla | 5 | 3 | 2 | 0 | 8:4 | 4 | 11 |
| 5 |
|
Barcelona | 5 | 3 | 1 | 1 | 12:6 | 6 | 10 |
| 6 |
|
Almería | 5 | 3 | 1 | 1 | 7:5 | 2 | 10 |
| 7 |
|
Atlético | 5 | 3 | 0 | 2 | 11:4 | 7 | 9 |
| 8 |
|
Getafe | 5 | 2 | 2 | 1 | 5:4 | 1 | 8 |
| 9 |
|
Mallorca | 5 | 2 | 2 | 1 | 5:5 | 0 | 8 |
| 10 |
|
Espanyol | 5 | 2 | 1 | 2 | 4:5 | -1 | 7 |
| 11 |
|
Valladolid | 5 | 2 | 0 | 3 | 5:6 | -1 | 6 |
| 12 |
|
Athletic | 5 | 1 | 2 | 2 | 4:5 | -1 | 5 |
| 13 |
|
Deportivo | 5 | 1 | 2 | 2 | 4:6 | -2 | 5 |
| 14 |
|
Osasuna | 5 | 0 | 4 | 1 | 2:3 | -1 | 4 |
| 15 |
|
Numancia | 5 | 1 | 1 | 3 | 5:8 | -3 | 4 |
| 16 |
|
RC Recreativo | 5 | 1 | 1 | 3 | 2:7 | -5 | 4 |
| 17 |
|
Málaga | 5 | 1 | 1 | 3 | 2:8 | -6 | 4 |
| 18 |
|
Betis | 5 | 0 | 2 | 3 | 3:6 | -3 | 2 |
| 19 |
|
Real Racing | 5 | 0 | 2 | 3 | 3:8 | -5 | 2 |
| 20 |
|
Sporting | 5 | 0 | 0 | 5 | 6:20 | -14 | 0 |
| Champions League | |
| CL Ronda previa | |
| Europa League | |
| Descenso |
