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| 04.12.2010 | 18:00 | Levante | - | Atlético | 2:0 (1:0) | |
| 20:45 | Osasuna | - | Barcelona | 0:3 (0:1) | ||
| 22:00 | Real Madrid | - | Valencia | 2:0 (0:0) | ||
| 05.12.2010 | 17:00 | Getafe | - | Mallorca | 3:0 (2:0) | |
| 17:00 | Almería | - | Zaragoza | 1:1 (0:0) | ||
| 17:00 | Espanyol | - | Sporting | 1:0 (0:0) | ||
| 17:00 | Málaga | - | Real Racing | 4:1 (2:1) | ||
| 19:00 | Villarreal | - | Sevilla | 1:0 (1:0) | ||
| 21:00 | Real Sociedad | - | Athletic | 2:0 (1:0) | ||
| 06.12.2010 | 21:00 | Deportivo | - | Hércules CF | 1:0 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta | 1.ª parte | 2.ª parte |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Barcelona | 14 | 12 | 1 | 1 | 41:8 | 33 | 37 |
| 2 |
|
Real Madrid | 14 | 11 | 2 | 1 | 35:11 | 24 | 35 |
| 3 |
|
Villarreal | 14 | 9 | 3 | 2 | 27:12 | 15 | 30 |
| 4 |
|
Espanyol | 14 | 9 | 1 | 4 | 16:15 | 1 | 28 |
| 5 |
|
Valencia | 14 | 7 | 3 | 4 | 19:15 | 4 | 24 |
| 6 |
|
Real Sociedad | 14 | 7 | 1 | 6 | 21:19 | 2 | 22 |
| 7 |
|
Mallorca | 14 | 6 | 3 | 5 | 15:16 | -1 | 21 |
| 8 |
|
Getafe | 14 | 6 | 2 | 6 | 22:20 | 2 | 20 |
| 9 |
|
Sevilla | 14 | 6 | 2 | 6 | 20:23 | -3 | 20 |
| 10 |
|
Atlético | 14 | 6 | 2 | 6 | 22:19 | 3 | 20 |
| 11 |
|
Athletic | 14 | 6 | 1 | 7 | 21:25 | -4 | 19 |
| 12 |
|
Deportivo | 14 | 4 | 5 | 5 | 12:16 | -4 | 17 |
| 13 |
|
Osasuna | 14 | 4 | 3 | 7 | 12:17 | -5 | 15 |
| 14 |
|
Hércules CF | 14 | 4 | 3 | 7 | 14:21 | -7 | 15 |
| 15 |
|
Real Racing | 14 | 4 | 2 | 8 | 12:23 | -11 | 14 |
| 16 |
|
Levante | 14 | 4 | 2 | 8 | 16:23 | -7 | 14 |
| 17 |
|
Málaga | 14 | 4 | 1 | 9 | 19:28 | -9 | 13 |
| 18 |
|
Sporting | 14 | 2 | 4 | 8 | 11:22 | -11 | 10 |
| 19 |
|
Almería | 14 | 1 | 7 | 6 | 10:21 | -11 | 10 |
| 20 |
|
Zaragoza | 14 | 1 | 6 | 7 | 13:24 | -11 | 9 |
| Champions League | |
| CL Ronda previa | |
| Europa League | |
| Descenso |
