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| 23.10.2021 | 15:00 | Paris FC | - | Toulouse | 2:2 (2:0) | |
| 19:00 | AC Ajaccio | - | AS Nancy Lorraine | 2:0 (1:0) | ||
| 19:00 | Havre AC | - | Pau FC | 1:0 (1:0) | ||
| 19:00 | Guingamp | - | Nîmes Olympique | 3:1 (1:0) | ||
| 19:00 | Chamois Niortais | - | Rodez AF | 0:2 (0:1) | ||
| 19:00 | FC Sochaux | - | US Quevilly-Rouen | 1:1 (0:1) | ||
| 19:00 | Grenoble Foot 38 | - | Dijon FCO | 1:2 (1:0) | ||
| 19:00 | Amiens SC | - | Valenciennes FC | 3:0 (1:0) | ||
| 19:00 | USL Dunkerque | - | Caen | 1:1 (0:0) | ||
| 25.10.2021 | 20:45 | AJ Auxerre | - | Bastia | 1:0 (1:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Toulouse | 13 | 8 | 4 | 1 | 30:11 | 19 | 28 |
| 2 |
|
FC Sochaux | 13 | 8 | 3 | 2 | 14:7 | 7 | 27 |
| 3 |
|
AC Ajaccio | 13 | 7 | 4 | 2 | 16:7 | 9 | 25 |
| 4 |
|
Havre AC | 13 | 6 | 6 | 1 | 14:7 | 7 | 24 |
| 5 |
|
AJ Auxerre | 13 | 6 | 5 | 2 | 19:13 | 6 | 23 |
| 6 |
|
Paris FC | 13 | 5 | 3 | 5 | 16:15 | 1 | 18 |
| 7 |
|
Chamois Niortais | 13 | 5 | 3 | 5 | 13:12 | 1 | 18 |
|
Pau FC | 13 | 5 | 3 | 5 | 13:12 | 1 | 18 | |
| 9 |
|
Guingamp | 13 | 4 | 5 | 4 | 14:15 | -1 | 17 |
| 10 |
|
Caen | 13 | 4 | 4 | 5 | 16:15 | 1 | 16 |
| 11 |
|
Rodez AF | 13 | 4 | 4 | 5 | 13:15 | -2 | 16 |
| 12 |
|
US Quevilly-Rouen | 13 | 4 | 4 | 5 | 13:16 | -3 | 16 |
| 13 |
|
Dijon FCO | 13 | 5 | 1 | 7 | 14:19 | -5 | 16 |
| 14 |
|
Grenoble Foot 38 | 13 | 4 | 3 | 6 | 13:18 | -5 | 15 |
| 15 |
|
Valenciennes FC | 13 | 4 | 3 | 6 | 11:20 | -9 | 15 |
| 16 |
|
Nîmes Olympique | 13 | 3 | 5 | 5 | 15:17 | -2 | 14 |
| 17 |
|
USL Dunkerque | 13 | 3 | 4 | 6 | 13:17 | -4 | 13 |
| 18 |
|
Amiens SC | 13 | 2 | 6 | 5 | 14:16 | -2 | 12 |
| 19 |
|
Bastia | 13 | 2 | 5 | 6 | 9:14 | -5 | 11 |
| 20 |
|
AS Nancy Lorraine | 13 | 1 | 5 | 7 | 9:23 | -14 | 8 |
| Ascenso | |
| Playoff | |
| Permanencia | |
| Descenso |
