| 1. Jornada | 15.08.2021 | Newcastle United | - | West Ham United | 2:4 | ||||
| 4. Jornada | 11.09.2021 | Manchester United | - | Newcastle United | 4:1 | ||||
| 5. Jornada | 17.09.2021 | Newcastle United | - | Leeds United | 1:1 | ||||
| 6. Jornada | 25.09.2021 | Watford FC | - | Newcastle United | 1:1 | ||||
| 7. Jornada | 02.10.2021 | Wolverhampton Wanderers | - | Newcastle United | 2:1 |  |
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| 8. Jornada | 17.10.2021 | Newcastle United | - | Tottenham Hotspur | 2:3 | |
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| 9. Jornada | 23.10.2021 | Crystal Palace | - | Newcastle United | 1:1 | ||||
| 10. Jornada | 30.10.2021 | Newcastle United | - | Chelsea | 0:3 | ||||
| 11. Jornada | 06.11.2021 | Brighton & Hove Albion | - | Newcastle United | 1:1 | ||||
| 12. Jornada | 20.11.2021 | Newcastle United | - | Brentford FC | 3:3 | ||||
| 14. Jornada | 30.11.2021 | Newcastle United | - | Norwich City | 1:1 |  |
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| 18. Jornada | 19.12.2021 | Newcastle United | - | Manchester City | 0:4 | ||||
| 23. Jornada | 22.01.2022 | Leeds United | - | Newcastle United | 0:1 |
Inglaterra