| 1. Jornada | 24.07.2022 | KV Mechelen | - | Royal Antwerp FC | 0:2 |  |
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| 2. Jornada | 31.07.2022 | Royal Antwerp FC | - | SV Zulte Waregem | 1:0 | ||||
| 3. Jornada | 07.08.2022 | Royal Antwerp FC | - | Oud-Heverlee Leuven | 4:2 | |
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| 4. Jornada | 14.08.2022 | KAS Eupen | - | Royal Antwerp FC | 0:1 | ||||
| 6. Jornada | 28.08.2022 | Gante | - | Royal Antwerp FC | 1:2 | |
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| 11. Jornada | 07.10.2022 | Royal Antwerp FC | - | Sint-Truidense VV | 2:0 | ||||
| 12. Jornada | 16.10.2022 | Standard Liège | - | Royal Antwerp FC | 3:0 | ||||
| 13. Jornada | 20.10.2022 | Royal Antwerp FC | - | KV Oostende | 3:0 | |
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| 14. Jornada | 23.10.2022 | Royal Antwerp FC | - | KRC Genk | 1:3 | ||||
| 15. Jornada | 30.10.2022 | Sporting Charleroi | - | Royal Antwerp FC | 1:0 | ||||
| 16. Jornada | 06.11.2022 | Royal Antwerp FC | - | RSC Anderlecht | 0:0 | ||||
| 17. Jornada | 13.11.2022 | Club Brugge KV | - | Royal Antwerp FC | 2:2 | |
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| 18. Jornada | 27.12.2022 | KVC Westerlo | - | Royal Antwerp FC | 3:3 | |
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| 19. Jornada | 07.01.2023 | Royal Antwerp FC | - | Gante | 2:0 |
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