| 5. Jornada | 06.09.1980 | Southampton | - | Brighton & Hove Albion | 3:1 | ||||
| 6. Jornada | 13.09.1980 | Norwich City | - | Southampton | 1:0 | ||||
| 7. Jornada | 20.09.1980 | Southampton | - | Liverpool | 2:2 |  |
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| 8. Jornada | 27.09.1980 | West Bromwich Albion | - | Southampton | 2:1 | ||||
| 10. Jornada | 07.10.1980 | Southampton | - | Wolverhampton Wanderers | 4:2 | ||||
| 11. Jornada | 11.10.1980 | Southampton | - | Stoke City | 1:2 | ||||
| 12. Jornada | 18.10.1980 | Middlesbrough | - | Southampton | 1:1 | ||||
| 13. Jornada | 21.10.1980 | Crystal Palace | - | Southampton | 3:2 | ||||
| 14. Jornada | 25.10.1980 | Southampton | - | Aston Villa | 1:2 | ||||
| 15. Jornada | 01.11.1980 | Nottingham Forest | - | Southampton | 2:1 | ||||
| 16. Jornada | 08.11.1980 | Southampton | - | Ipswich Town | 3:3 | |
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| 17. Jornada | 11.11.1980 | Southampton | - | Arsenal | 3:1 | ||||
| 18. Jornada | 15.11.1980 | Manchester City | - | Southampton | 3:0 |
Inglaterra