| 1. Jornada | 27.08.1921 | Everton | - | Manchester United | 5:0 | ||||
| 8. Jornada | 01.10.1921 | Manchester United | - | Preston North End | 1:1 | ||||
| 9. Jornada | 08.10.1921 | Tottenham Hotspur | - | Manchester United | 2:2 | ||||
| 10. Jornada | 15.10.1921 | Manchester United | - | Tottenham Hotspur | 2:1 | ||||
| 11. Jornada | 22.10.1921 | Manchester City | - | Manchester United | 4:1 | ||||
| 29. Jornada | 18.02.1922 | Birmingham FC | - | Manchester United | 0:1 | ||||
| 30. Jornada | 25.02.1922 | Manchester United | - | Birmingham FC | 1:1 | ||||
| 27. Jornada | 27.02.1922 | Huddersfield Town | - | Manchester United | 1:1 | ||||
| 32. Jornada | 11.03.1922 | Manchester United | - | Arsenal | 1:0 | ||||
| 33. Jornada | 18.03.1922 | Manchester United | - | Blackburn Rovers | 0:1 | ||||
| 34. Jornada | 25.03.1922 | Blackburn Rovers | - | Manchester United | 3:0 | ||||
| 35. Jornada | 01.04.1922 | Manchester United | - | Bolton Wanderers | 0:1 | ||||
| 31. Jornada | 05.04.1922 | Arsenal | - | Manchester United | 3:1 | ||||
| 36. Jornada | 08.04.1922 | Bolton Wanderers | - | Manchester United | 1:0 | ||||
| 38. Jornada | 15.04.1922 | Manchester United | - | Oldham Athletic | 0:3 |
Gales