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| 20.08.2022 | 23:00 | Colón de Santa Fe | - | Tigre | 2:1 (1:0) | |
| 21.08.2022 | 01:30 | Huracán | - | Newell's Old Boys | 1:0 (0:0) | |
| 18:00 | CA Lanús | - | Arsenal de Sarandí | 1:0 (0:0) | ||
| 20:30 | Godoy Cruz | - | Independiente | 1:1 (0:1) | ||
| 23:00 | River Plate | - | Central Córdoba SdE | 3:0 (2:0) | ||
| 22.08.2022 | 01:30 | Defensa y Justicia | - | Boca Juniors | 0:1 (0:0) | |
| 21:30 | Estudiantes | - | Unión de Santa Fe | 1:0 (0:0) | ||
| 21:30 | Rosario Central | - | Banfield | 0:1 (0:1) | ||
| 23.08.2022 | 00:00 | Racing Club | - | San Lorenzo | 1:2 (0:0) | |
| 02:30 | Platense | - | Talleres de Córdoba | 0:0 (0:0) | ||
| 02:30 | Vélez Sarsfield | - | Sarmiento de Junín | 1:1 (0:1) | ||
| 24.08.2022 | 00:00 | Patronato de Paraná | - | Argentinos Juniors | 0:0 (0:0) | |
| 02:30 | Atlético Tucumán | - | Barracas Central | 4:0 (1:0) | ||
| 02:30 | Gimnasia de La Plata | - | Aldosivi | 0:0 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Atlético Tucumán | 15 | 9 | 5 | 1 | 18:6 | 12 | 32 |
| 2 |
|
Gimnasia de La Plata | 15 | 8 | 5 | 2 | 16:7 | 9 | 29 |
| 3 |
|
Huracán | 15 | 7 | 6 | 2 | 18:11 | 7 | 27 |
| 4 |
|
Argentinos Juniors | 15 | 8 | 3 | 4 | 18:12 | 6 | 27 |
| 5 |
|
River Plate | 15 | 7 | 4 | 4 | 24:13 | 11 | 25 |
| 6 |
|
Godoy Cruz | 15 | 7 | 4 | 4 | 18:13 | 5 | 25 |
| 7 |
|
Racing Club | 15 | 6 | 6 | 3 | 22:13 | 9 | 24 |
| 8 |
|
San Lorenzo | 15 | 5 | 8 | 2 | 21:16 | 5 | 23 |
| 9 |
|
Patronato de Paraná | 15 | 6 | 5 | 4 | 22:18 | 4 | 23 |
| 10 |
|
Boca Juniors | 15 | 7 | 2 | 6 | 19:20 | -1 | 23 |
| 11 |
|
Platense | 15 | 5 | 7 | 3 | 15:13 | 2 | 22 |
| 12 |
|
Unión de Santa Fe | 15 | 6 | 4 | 5 | 22:24 | -2 | 22 |
| 13 |
|
Newell's Old Boys | 15 | 5 | 5 | 5 | 13:14 | -1 | 20 |
| 14 |
|
Estudiantes | 15 | 5 | 4 | 6 | 15:17 | -2 | 19 |
| 15 |
|
Tigre | 15 | 4 | 6 | 5 | 21:20 | 1 | 18 |
| 16 |
|
Arsenal de Sarandí | 15 | 3 | 9 | 3 | 15:16 | -1 | 18 |
| 17 |
|
Banfield | 15 | 4 | 6 | 5 | 14:15 | -1 | 18 |
| 18 |
|
Sarmiento de Junín | 15 | 5 | 3 | 7 | 16:20 | -4 | 18 |
| 19 |
|
Colón de Santa Fe | 15 | 4 | 6 | 5 | 13:17 | -4 | 18 |
| 20 |
|
Rosario Central | 15 | 5 | 3 | 7 | 11:15 | -4 | 18 |
| 21 |
|
Central Córdoba SdE | 15 | 5 | 2 | 8 | 17:21 | -4 | 17 |
| 22 |
|
Barracas Central | 15 | 4 | 5 | 6 | 17:24 | -7 | 17 |
| 23 |
|
Talleres de Córdoba | 15 | 3 | 6 | 6 | 13:16 | -3 | 15 |
| 24 |
|
Defensa y Justicia | 15 | 3 | 6 | 6 | 12:17 | -5 | 15 |
| 25 |
|
Independiente | 15 | 3 | 5 | 7 | 14:18 | -4 | 14 |
| 26 |
|
Aldosivi | 15 | 3 | 3 | 9 | 10:23 | -13 | 12 |
| 27 |
|
Vélez Sarsfield | 15 | 1 | 8 | 6 | 16:21 | -5 | 11 |
| 28 |
|
CA Lanús | 15 | 2 | 4 | 9 | 12:22 | -10 | 10 |
