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| 14.01.2017 | 16:00 | Granada B | - | CD El Ejido 2012 | 3:1 (1:1) | |
| 15.01.2017 | 12:00 | Extremadura UD | - | FC Jumilla | 4:0 (1:0) | |
| 12:15 | UD Melilla | - | La Roda CF | 2:1 (2:0) | ||
| 16:00 | Real Jaén | - | RC Recreativo | 1:3 (1:2) | ||
| 17:00 | Real Murcia | - | CF Villanovense | 2:1 (1:1) | ||
| 17:00 | Atlético Sanluqueño CF | - | RB Linense | 0:0 (0:0) | ||
| 17:00 | Marbella FC | - | Linares Deportivo | 2:0 (1:0) | ||
| 17:00 | FC Cartagena | - | Córdoba B | 1:2 (1:1) | ||
| 17:00 | San Fernando CD | - | Atlético Mancha Real | 1:1 (1:0) | ||
| 17:00 | Lorca FC | - | Mérida AD | 2:0 (1:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Cartagena | 21 | 12 | 5 | 4 | 31:16 | 15 | 41 |
| 2 |
|
Lorca FC | 21 | 12 | 5 | 4 | 34:24 | 10 | 41 |
| 3 |
|
Marbella FC | 21 | 12 | 4 | 5 | 31:23 | 8 | 40 |
| 4 |
|
CF Villanovense | 21 | 10 | 6 | 5 | 35:20 | 15 | 36 |
| 5 |
|
UD Melilla | 21 | 9 | 8 | 4 | 25:15 | 10 | 35 |
| 6 |
|
FC Jumilla | 21 | 10 | 5 | 6 | 18:15 | 3 | 35 |
| 7 |
|
Real Murcia | 21 | 10 | 4 | 7 | 20:18 | 2 | 34 |
| 8 |
|
Mérida AD | 21 | 9 | 4 | 8 | 25:23 | 2 | 31 |
| 9 |
|
San Fernando CD | 21 | 9 | 4 | 8 | 25:26 | -1 | 31 |
| 10 |
|
Granada B | 21 | 8 | 5 | 8 | 32:24 | 8 | 29 |
| 11 |
|
Linares Deportivo | 21 | 8 | 5 | 8 | 24:22 | 2 | 29 |
| 12 |
|
Atlético Mancha Real | 21 | 8 | 4 | 9 | 31:35 | -4 | 28 |
| 13 |
|
Córdoba B | 21 | 6 | 6 | 9 | 22:24 | -2 | 24 |
| 14 |
|
Real Jaén | 21 | 4 | 11 | 6 | 23:24 | -1 | 23 |
| 15 |
|
RB Linense | 21 | 5 | 8 | 8 | 22:31 | -9 | 23 |
| 16 |
|
RC Recreativo | 21 | 4 | 10 | 7 | 17:23 | -6 | 22 |
| 17 |
|
CD El Ejido 2012 | 21 | 6 | 4 | 11 | 24:33 | -9 | 22 |
| 18 |
|
Extremadura UD | 21 | 4 | 6 | 11 | 18:34 | -16 | 18 |
| 19 |
|
La Roda CF | 21 | 3 | 8 | 10 | 24:31 | -7 | 17 |
| 20 |
|
Atlético Sanluqueño CF | 21 | 2 | 6 | 13 | 15:35 | -20 | 12 |
| Playoff | |
| Playoff | |
| Permanencia | |
| Descenso |
