| 20. Jornada | 01.02.2021 | Reggina 1914 | - | US Salernitana 1919 | 0:0 |  |
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| 21. Jornada | 06.02.2021 | Delfino Pescara | - | Reggina 1914 | 0:2 |  |
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| 22. Jornada | 10.02.2021 | Reggina 1914 | - | Virtus Entella | 1:0 | |
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| 23. Jornada | 15.02.2021 | Cosenza Calcio | - | Reggina 1914 | 2:2 | ||||
| 25. Jornada | 27.02.2021 | SPAL 2013 Ferrara | - | Reggina 1914 | 1:4 | |
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| 26. Jornada | 02.03.2021 | Reggina 1914 | - | Empoli | 0:3 | ||||
| 27. Jornada | 06.03.2021 | AC Pisa | - | Reggina 1914 | 0:0 | ||||
| 29. Jornada | 16.03.2021 | Brescia Calcio | - | Reggina 1914 | 1:0 | ||||
| 30. Jornada | 21.03.2021 | Reggina 1914 | - | Chievo | 1:1 | |
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| 31. Jornada | 02.04.2021 | Venezia FC | - | Reggina 1914 | 0:2 | ||||
| 32. Jornada | 05.04.2021 | AS Cittadella | - | Reggina 1914 | 1:1 | ||||
| 33. Jornada | 11.04.2021 | Reggina 1914 | - | L.R. Vicenza Virtus | 3:0 | ||||
| 34. Jornada | 17.04.2021 | Reggina 1914 | - | AC Reggiana 1919 | 2:1 | |
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| 36. Jornada | 04.05.2021 | Reggina 1914 | - | Ascoli Calcio | 2:2 | |
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| 37. Jornada | 07.05.2021 | US Lecce | - | Reggina 1914 | 2:2 | |
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| 38. Jornada | 10.05.2021 | Reggina 1914 | - | Frosinone | 0:4 |
Italia