| 3. Jornada | 13.09.2021 | US Triestina | - | Piacenza Calcio | 2:2 | ||||
| 4. Jornada | 19.09.2021 | Calcio Padova | - | US Triestina | 2:0 | ||||
| 2. Jornada | 22.09.2021 | Juventus II | - | US Triestina | 2:1 | ||||
| 5. Jornada | 26.09.2021 | US Triestina | - | Calcio Lecco 1912 | 2:0 | ||||
| 6. Jornada | 29.09.2021 | AC Pro Sesto | - | US Triestina | 0:1 |  |
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| 7. Jornada | 03.10.2021 | US Triestina | - | UC AlbinoLeffe | 2:3 | ||||
| 8. Jornada | 10.10.2021 | Virtus Verona | - | US Triestina | 0:0 | ||||
| 9. Jornada | 17.10.2021 | US Triestina | - | US Fiorenzuola | 1:0 | ||||
| 10. Jornada | 20.10.2021 | US Triestina | - | Mantova 1911 SSD | 2:1 | ||||
| 12. Jornada | 31.10.2021 | US Triestina | - | Feralpisalò | 1:1 | ||||
| 13. Jornada | 06.11.2021 | US Pergolettese | - | US Triestina | 0:1 | ||||
| 17. Jornada | 05.12.2021 | Pro Vercelli | - | US Triestina | 1:2 | |
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| 18. Jornada | 12.12.2021 | US Triestina | - | Giana Erminio | 2:1 | |
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| 20. Jornada | 21.12.2021 | Seregno | - | US Triestina | 0:1 | ||||
| 23. Jornada | 23.01.2022 | US Triestina | - | Calcio Padova | 0:2 | ||||
| 19. Jornada | 26.01.2022 | FC Südtirol | - | US Triestina | 1:0 | |
Italia