| 1. Jornada | 21.08.2021 | RSC Anderlecht [Sub 18] | - | KV Mechelen [Sub 18] | 2:1 | ||||
| 2. Jornada | 28.08.2021 | Sporting Charleroi [Sub 18] | - | RSC Anderlecht [Sub 18] | 1:4 | ||||
| 4. Jornada | 11.09.2021 | KRC Genk [Sub 18] | - | RSC Anderlecht [Sub 18] | 2:2 | ||||
| 5. Jornada | 18.09.2021 | RSC Anderlecht [Sub 18] | - | KAA Gent [Sub 18] | 5:2 | ||||
| 6. Jornada | 25.09.2021 | SV Zulte Waregem [Sub 18] | - | RSC Anderlecht [Sub 18] | 3:4 | ||||
| 7. Jornada | 02.10.2021 | RSC Anderlecht [Sub 18] | - | Cercle Brugge [Sub 18] | 6:1 | ||||
| 9. Jornada | 16.10.2021 | RSC Anderlecht [Sub 18] | - | Oud-Heverlee Leuven [Sub 18] | 2:2 | ||||
| 10. Jornada | 23.10.2021 | Standard Liège [Sub 18] | - | RSC Anderlecht [Sub 18] | 3:1 |  |
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| 14. Jornada | 27.11.2021 | KV Mechelen [Sub 18] | - | RSC Anderlecht [Sub 18] | 2:0 | ||||
| 8. Jornada | 01.12.2021 | Royal Antwerp FC [Sub 18] | - | RSC Anderlecht [Sub 18] | 1:2 | |
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| 13. Jornada | 26.02.2022 | Sint-Truidense VV [Sub 18] | - | RSC Anderlecht [Sub 18] | 0:1 | |
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| 22. Jornada | 12.03.2022 | Oud-Heverlee Leuven [Sub 18] | - | RSC Anderlecht [Sub 18] | 1:2 | |
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| 25. Jornada | 02.04.2022 | Club Brugge KV [Sub 18] | - | RSC Anderlecht [Sub 18] | 3:1 |
Bélgica