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| 30.01.2022 | 12:30 | Cesena FC | - | Olbia Calcio | 3:0 (2:0) | |
| 14:30 | AS Gubbio | - | US Grosseto FC | 0:0 (0:0) | ||
| 14:30 | Lucchese | - | Ancona 1905 | 2:2 (1:2) | ||
| 14:30 | Fermana FC | - | Carrarese Calcio | 0:0 (0:0) | ||
| 14:30 | Imolese Calcio | - | Teramo Calcio | 1:0 (0:0) | ||
| 14:30 | Aquila Montevarchi | - | US Pontedera | 0:0 (0:0) | ||
| 14:30 | AC Reggiana 1919 | - | ACN Siena 1904 | 1:0 (1:0) | ||
| 14:30 | Virtus Entella | - | Modena FC | 0:2 (0:0) | ||
| 14:30 | Viterbese | - | Delfino Pescara | 1:3 (0:3) | ||
| 14:30 | US Pistoiese | - | Vis Pesaro | 0:1 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Modena FC | 24 | 18 | 4 | 2 | 46:17 | 29 | 58 |
| 2 |
|
AC Reggiana 1919 | 24 | 16 | 7 | 1 | 45:14 | 31 | 55 |
| 3 |
|
Cesena FC | 24 | 12 | 9 | 3 | 31:15 | 16 | 45 |
| 4 |
|
Ancona 1905 | 24 | 12 | 6 | 6 | 46:28 | 18 | 42 |
| 5 |
|
Delfino Pescara | 24 | 11 | 9 | 4 | 38:27 | 11 | 42 |
| 6 |
|
Virtus Entella | 24 | 11 | 6 | 7 | 41:28 | 13 | 39 |
| 7 |
|
AS Gubbio | 24 | 8 | 10 | 6 | 33:26 | 7 | 34 |
| 8 |
|
Carrarese Calcio | 24 | 7 | 11 | 6 | 26:29 | -3 | 32 |
| 9 |
|
Lucchese | 24 | 7 | 10 | 7 | 25:25 | 0 | 31 |
| 10 |
|
Vis Pesaro | 24 | 7 | 10 | 7 | 22:29 | -7 | 31 |
| 11 |
|
Olbia Calcio | 24 | 8 | 5 | 11 | 28:33 | -5 | 29 |
| 12 |
|
US Pontedera | 24 | 8 | 5 | 11 | 27:39 | -12 | 29 |
| 13 |
|
ACN Siena 1904 | 24 | 7 | 6 | 11 | 27:29 | -2 | 27 |
| 14 |
|
Aquila Montevarchi | 24 | 7 | 4 | 13 | 26:42 | -16 | 25 |
| 15 |
|
Imolese Calcio | 24 | 6 | 8 | 10 | 30:33 | -3 | 24 |
| 16 |
|
Fermana FC | 24 | 5 | 8 | 11 | 19:31 | -12 | 23 |
| 17 |
|
Teramo Calcio | 24 | 5 | 7 | 12 | 22:42 | -20 | 22 |
| 18 |
|
US Grosseto FC | 24 | 3 | 10 | 11 | 18:28 | -10 | 19 |
| 19 |
|
Viterbese | 24 | 3 | 10 | 11 | 25:36 | -11 | 19 |
| 20 |
|
US Pistoiese | 24 | 3 | 7 | 14 | 17:41 | -24 | 16 |
| Ascenso | |
| Playoff | |
| Permanencia | |
| Descenso |
